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Lrrc34 Gene Detail
Summary
  • Symbol
    Lrrc34
  • Name
    leucine rich repeat containing 34
  • Synonyms
    1700007J06Rik, Spata34
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919077
    NCBI Gene: 71827
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:30678416-30701967 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 14.27 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    91 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919077
 protein coding gene Chr3:30678416-30702018 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027123
 protein coding gene Chr3:28122874-28145641 (-)
A/J MGP_AJ_G0027083
 protein coding gene Chr3:27749683-27774943 (-)
AKR/J MGP_AKRJ_G0027052
 protein coding gene Chr3:28168932-28197060 (-)
BALB/cJ MGP_BALBcJ_G0027095
 protein coding gene Chr3:27448071-27471621 (-)
C3H/HeJ MGP_C3HHeJ_G0026837
 protein coding gene Chr3:28202810-28226527 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027541
 protein coding gene Chr3:29621936-29648178 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024902
 protein coding gene Chr3:25664646-25688785 (-)
CAST/EiJ MGP_CASTEiJ_G0026291
 protein coding gene Chr3:28101027-28126965 (-)
CBA/J MGP_CBAJ_G0026815
 protein coding gene Chr3:30357950-30385499 (-)
DBA/2J MGP_DBA2J_G0026949
 protein coding gene Chr3:27312340-27335632 (-)
FVB/NJ MGP_FVBNJ_G0026917
 protein coding gene Chr3:26755222-26778392 (-)
LP/J MGP_LPJ_G0027060
 protein coding gene Chr3:28805103-28830273 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026937
 protein coding gene Chr3:32954045-32979422 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027600
 protein coding gene Chr3:27916823-27943859 (-)
PWK/PhJ MGP_PWKPhJ_G0026024
 protein coding gene Chr3:26809760-26833895 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025836
 protein coding gene Chr3:27438065-27461960 (-)
WSB/EiJ MGP_WSBEiJ_G0026365
 protein coding gene Chr3:28022565-28047176 (-)



Homology
more
  • Human Ortholog
    LRRC34, leucine rich repeat containing 34
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC34, leucine rich repeat containing 34
  • Links
    NCBI Gene ID: 151827
    neXtProt AC: NX_Q8IZ02
    UniProt: Q8IZ02

  • Chr Location
    3q26.2; chr3:169793003-169812986 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Homozygous knockout does not affect fertility or spermatogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    859
  • Tissues
    100
  • cDNA Data
    15
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71827 NCBI Gene Model | MGI Sequence Detail 23552 C57BL/6J ±  kb
transcript NM_027941 RefSeq | MGI Sequence Detail 1978 Not Specified  
polypeptide Q9DAM1 UniProt | EBI | MGI Sequence Detail 415 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 15
    Primer pair 1
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 2
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:339453 Nolte J, Lrrc34 Interacts with Oct4 and Has an Impact on Telomere Length in Mouse Embryonic Stem Cells. Stem Cells Dev. 2021 Nov;30(22):1093-1102
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory