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Osbpl7 Gene Detail
Summary
  • Symbol
    Osbpl7
  • Name
    oxysterol binding protein-like 7
  • Synonyms
    4933437E18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918490
    NCBI Gene: 71240
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:96941459-96959730 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 60.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    231 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918490
 protein coding gene Chr11:96941454-96959730 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019023
 protein coding gene Chr11:99431595-99449696 (+)
A/J MGP_AJ_G0018991
 protein coding gene Chr11:95359897-95378360 (+)
AKR/J MGP_AKRJ_G0018961
 protein coding gene Chr11:98316156-98337352 (+)
BALB/cJ MGP_BALBcJ_G0018964
 protein coding gene Chr11:95848860-95867504 (+)
C3H/HeJ MGP_C3HHeJ_G0018778
 protein coding gene Chr11:98427061-98446162 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019416
 protein coding gene Chr11:102512514-102531872 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017047
 protein coding gene Chr11:92821839-92840232 (+)
CAST/EiJ MGP_CASTEiJ_G0018331
 protein coding gene Chr11:99283795-99303298 (+)
CBA/J MGP_CBAJ_G0018749
 protein coding gene Chr11:106724845-106747515 (+)
DBA/2J MGP_DBA2J_G0018857
 protein coding gene Chr11:94910442-94928358 (+)
FVB/NJ MGP_FVBNJ_G0018846
 protein coding gene Chr11:94389344-94408714 (+)
LP/J MGP_LPJ_G0018927
 protein coding gene Chr11:99956743-99976512 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018873
 protein coding gene Chr11:106643054-106660433 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019456
 protein coding gene Chr11:98610111-98629561 (+)
PWK/PhJ MGP_PWKPhJ_G0018103
 protein coding gene Chr11:95883551-95901458 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017893
 protein coding gene Chr11:98336204-98355085 (+)
WSB/EiJ MGP_WSBEiJ_G0018381
 protein coding gene Chr11:98515884-98537707 (+)



Homology
more
  • Human Ortholog
    OSBPL7, oxysterol binding protein like 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OSBPL7, oxysterol binding protein like 7
  • Synonyms
    ORP7
  • Links
    NCBI Gene ID: 114881
    neXtProt AC: NX_Q9BZF2
    UniProt: Q9BZF2

  • Chr Location
    17q21.32; chr17:47807372-47821803 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    743
  • Tissues
    28
  • cDNA Data
    8
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 71240 NCBI Gene Model | MGI Sequence Detail 18272 C57BL/6J ±  kb
transcript NM_001310509 RefSeq | MGI Sequence Detail 3594 C57BL/6  
polypeptide NP_001297438 RefSeq | MGI Sequence Detail 837 C57BL/6  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • InterPro Domains
    IPR000648 Oxysterol-binding protein
    IPR018494 Oxysterol-binding protein, conserved site
    IPR037239 Oxysterol-binding protein superfamily
    IPR011993 PH-like domain superfamily
    IPR001849 Pleckstrin homology domain
    IPR041680 Pleckstrin homology domain 8
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 14
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory