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Nudt4 Gene Detail
Summary
  • Symbol
    Nudt4
  • Name
    nudix hydrolase 4
  • Synonyms
    4933436C10Rik, DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P, nudix (nucleoside diphosphate linked moiety X)-type motif 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918457
    NCBI Gene: 71207
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:95382869-95400008 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 49.42 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    567 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918457
 protein coding gene Chr10:95382869-95400008 (-)
129S1/SvImJ ENSMUSG00200019313
 protein coding gene Chr10:91898427-91915564 (-)
A/J ENSMUSG00195014350
 protein coding gene Chr10:92324539-92341679 (-)
AKR/J ENSMUSG00220024896
 protein coding gene Chr10:91886249-91903388 (-)
BALB/cJ ENSMUSG00180009287
 protein coding gene Chr10:92327099-92344241 (-)
C3H/HeJ ENSMUSG00175005700
 protein coding gene Chr10:92232987-92248824 (-)
C57BL/6NJ ENSMUSG00215005501
 protein coding gene Chr10:91914129-91931268 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015752
 protein coding gene Chr10:89249469-89266724 (-)
CAST/EiJ ENSTCUG00005033668
 protein coding gene Chr10:91603428-91620379 (-)
CBA/J ENSMUSG00210022779
 protein coding gene Chr10:92062804-92079946 (-)
DBA/2J ENSMUSG00185040978
 protein coding gene Chr10:92274776-92291921 (-)
FVB/NJ ENSMUSG00205011501
 protein coding gene Chr10:91973585-91990610 (-)
JF1/MsJ ENSUMUG00000020158
 protein coding gene Chr10:93697585-93714714 (-)
LP/J ENSMUSG00230020043
 protein coding gene Chr10:94187077-94204211 (-)
NOD/ShiLtJ ENSMUSG00190018085
 protein coding gene Chr10:92312000-92329135 (-)
NZO/HlLtJ ENSMUSG00225021392
 protein coding gene Chr10:98430622-98447710 (-)
PWK/PhJ ENSLUMG00010005027
 protein coding gene Chr10:91956814-91973746 (-)
SPRET/EiJ ENSMSPG00010009968
 protein coding gene Chr10:93611418-93626381 (-)
WSB/EiJ ENSIUOG00005012552
 protein coding gene Chr10:92010824-92026828 (-)



Homology
more
  • Human Ortholog
    NUDT4, nudix hydrolase 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NUDT4, nudix hydrolase 4
  • Synonyms
    DIPP2, DIPP2alpha, DIPP-2B, DIPP2beta, HDCMB47P
  • Links
    NCBI Gene ID: 11163
    UniProt: Q9NZJ9

  • Chr Location
    12q22; chr12:93377883-93408146 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotype references
  • All Mutations and Alleles
    25
  • Chemically induced (other)
    1
  • Gene trapped
    20
  • Targeted
    3
  • Transposon induced
    1
  • Genomic Mutations
    2 involving Nudt4
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    11 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71207 NCBI Gene Model | MGI Sequence Detail 17140 C57BL/6J ±  kb
transcript NM_001358996 RefSeq | MGI Sequence Detail 3213 C57BL/6  
polypeptide Q8R2U6 UniProt | EBI | MGI Sequence Detail 179 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 5
References
more
  • Summaries
    All 45
    Gene Ontology 8
    Phenotypes 17
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory