About   Help   FAQ
Gmpr2 Gene Detail
Summary
  • Symbol
    Gmpr2
  • Name
    guanosine monophosphate reductase 2
  • Synonyms
    1810008P16Rik, 5730544D12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917903
    NCBI Gene: 105446
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:55909398-55916657 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 28.19 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    40 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917903
 protein coding gene Chr14:55909398-55935602 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021362
 protein coding gene Chr14:49713942-49721644 (+)
A/J MGP_AJ_G0021321
 protein coding gene Chr14:48721922-48728520 (+)
AKR/J MGP_AKRJ_G0021297
 protein coding gene Chr14:50469564-50476079 (+)
BALB/cJ MGP_BALBcJ_G0021325
 protein coding gene Chr14:48680999-48689637 (+)
C3H/HeJ MGP_C3HHeJ_G0021105
 protein coding gene Chr14:50153156-50160239 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021763
 protein coding gene Chr14:52203443-52210717 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019310
 protein coding gene Chr14:47094393-47100709 (+)
CAST/EiJ MGP_CASTEiJ_G0020624
 protein coding gene Chr14:46422419-46428928 (+)
CBA/J MGP_CBAJ_G0021072
 protein coding gene Chr14:53770674-53778951 (+)
DBA/2J MGP_DBA2J_G0021193
 protein coding gene Chr14:48445185-48451715 (+)
FVB/NJ MGP_FVBNJ_G0021175
 protein coding gene Chr14:47893534-47900049 (+)
LP/J MGP_LPJ_G0021267
 protein coding gene Chr14:50760657-50767628 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021199
 protein coding gene Chr14:53124154-53133119 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021790
 protein coding gene Chr14:49656274-49663995 (+)
PWK/PhJ MGP_PWKPhJ_G0020371
 protein coding gene Chr14:44978070-44984658 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020199
 protein coding gene Chr14:45663496-45669598 (+)
WSB/EiJ MGP_WSBEiJ_G0020677
 protein coding gene Chr14:49942047-49948582 (+)



Homology
more
  • Human Ortholog
    GMPR2, guanosine monophosphate reductase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GMPR2, guanosine monophosphate reductase 2
  • Synonyms
    GMPR 2
  • Links
    NCBI Gene ID: 51292
    neXtProt AC: NX_Q9P2T1
    UniProt: Q9P2T1

  • Chr Location
    14q12; chr14:24232422-24239242 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    9
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000002326 Ensembl Gene Model | MGI Sequence Detail 7260 C57BL/6J ±  kb
transcript ENSMUST00000002397 Ensembl | MGI Sequence Detail 1993 Not Applicable  
polypeptide ENSMUSP00000002397 Ensembl | MGI Sequence Detail 348 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 5
Other
Accession IDs
less
MGI:1916331, MGI:2145585
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory