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Dcp2 Gene Detail
Summary
  • Symbol
    Dcp2
  • Name
    decapping mRNA 2
  • Synonyms
    2410015D23Rik, 5730537H01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917890
    NCBI Gene: 70640
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:44513569-44558036 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 23.74 cM, cytoband B3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1532 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917890
 protein coding gene Chr18:44513567-44558036 (+)
129S1/SvImJ ENSMUSG00200028762
 protein coding gene Chr18:41554195-41598668 (+)
A/J ENSMUSG00195024580
 protein coding gene Chr18:41711708-41755950 (+)
AKR/J ENSMUSG00220020549
 protein coding gene Chr18:41673322-41717564 (+)
BALB/cJ ENSMUSG00180007724
 protein coding gene Chr18:42178854-42222934 (+)
C3H/HeJ ENSMUSG00175010410
 protein coding gene Chr18:41697592-41741668 (+)
C57BL/6NJ ENSMUSG00215007295
 protein coding gene Chr18:41399086-41443561 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022246
 protein coding gene Chr18:41366346-41412921 (+)
CAST/EiJ ENSTCUG00005013486
 protein coding gene Chr18:41215858-41260813 (+)
CBA/J ENSMUSG00210022480
 protein coding gene Chr18:41744572-41788653 (+)
DBA/2J ENSMUSG00185027343
 protein coding gene Chr18:41653304-41697382 (+)
FVB/NJ ENSMUSG00205013367
 protein coding gene Chr18:41265307-41309782 (+)
JF1/MsJ ENSUMUG00000018922
 protein coding gene Chr18:41756826-41801242 (+)
LP/J ENSMUSG00230028003
 protein coding gene Chr18:43743870-43788339 (+)
NOD/ShiLtJ ENSMUSG00190026427
 protein coding gene Chr18:41412199-41456288 (+)
NZO/HlLtJ ENSMUSG00225026930
 protein coding gene Chr18:43613725-43658194 (+)
PWK/PhJ ENSLUMG00010021088
 protein coding gene Chr18:41846703-41891492 (+)
SPRET/EiJ ENSMSPG00010012493
 protein coding gene Chr18:41998574-42037069 (+)
WSB/EiJ ENSIUOG00005008670
 protein coding gene Chr18:41370104-41414575 (+)



Homology
more
  • Human Ortholog
    DCP2, decapping mRNA 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DCP2, decapping mRNA 2
  • Synonyms
    NUDT20
  • Links
    NCBI Gene ID: 167227
    UniProt: Q8IU60

  • Chr Location
    5q22.2; chr5:112976702-113022195 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 5 alleles in 5 genetic backgrounds
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele are viable and fertile. Mice homozygous for a null allele exhibit male infertility with reduced sperm numbers and motility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    47
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    686
  • Tissues
    37
  • cDNA Data
    94
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000024472 Ensembl Gene Model | MGI Sequence Detail 44468 C57BL/6J ±  kb
    transcript ENSMUST00000025350 Ensembl | MGI Sequence Detail 8616 Not Applicable  
    polypeptide ENSMUSP00000025350 Ensembl | MGI Sequence Detail 422 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 96
      cDNA 94
      Primer pair 2
      Antibodies 5

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1913674, MGI:3035096
    References
    more
    • Summaries
      All 60
      Developmental Gene Expression 6
      Gene Ontology 11
      Phenotypes 18
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:346062 Perez RC, et al., TOB1 and TOB2 mark distinct RNA processing granules in differentiating lens fiber cells. J Mol Histol. 2024 Feb;55(1):121-138
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory