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Ube2v2 Gene Detail
Summary
  • Symbol
    Ube2v2
  • Name
    ubiquitin-conjugating enzyme E2 variant 2
  • Synonyms
    1110021H13Rik, 4632410D19Rik, 5730524P06Rik, MMS2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917870
    NCBI Gene: 70620
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:15368850-15412382 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 10.09 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1045 from dbSNP Build 142
  • Strain Annotations
    27
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917870
 protein coding gene Chr16:15368850-15413637 (-)
129S1/SvImJ ENSMUSG00200042799
 protein coding gene Chr16:12362779-12406338 (-)
129S1/SvImJ ENSMUSG00200020510
 protein coding gene Chr6:97579005-97580850 (+)
A/J ENSMUSG00195001879
 protein coding gene Chr6:97278154-97280014 (+)
A/J ENSMUSG00195028813
 protein coding gene Chr16:11920910-11964608 (-)
AKR/J ENSMUSG00220045286
 protein coding gene Chr16:12232125-12275821 (-)
AKR/J ENSMUSG00220021438
 protein coding gene Chr6:96194133-96195993 (+)
BALB/cJ ENSMUSG00180009751
 protein coding gene Chr6:97662469-97664315 (+)
BALB/cJ ENSMUSG00180029911
 protein coding gene Chr16:12161226-12204792 (-)
C3H/HeJ ENSMUSG00175036921
 protein coding gene Chr16:12307190-12350889 (-)
C3H/HeJ ENSMUSG00175016387
 protein coding gene Chr6:79762673-79764534 (-)
C57BL/6NJ ENSMUSG00215009261
 protein coding gene Chr6:97658970-97660831 (+)
C57BL/6NJ ENSMUSG00215032116
 protein coding gene Chr16:12028726-12072425 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020485
 protein coding gene Chr16:12094452-12133441 (-)
CAST/EiJ ENSTCUG00005044872
 protein coding gene Chr16:12206940-12250665 (-)
CBA/J ENSMUSG00210044044
 protein coding gene Chr16:12324112-12367808 (-)
CBA/J ENSMUSG00210003788
 protein coding gene Chr6:97468014-97469874 (+)
DBA/2J ENSMUSG00185025340
 protein coding gene Chr6:97949802-97951662 (+)
DBA/2J ENSMUSG00185027045
 protein coding gene Chr16:12269619-12313316 (-)
FVB/NJ ENSMUSG00205044065
 protein coding gene Chr16:12275961-12319655 (-)
JF1/MsJ ENSUMUG00000045940
 protein coding gene Chr16:12343517-12387345 (-)
LP/J ENSMUSG00230012437
 protein coding gene Chr6:99139168-99141028 (+)
LP/J ENSMUSG00230037578
 protein coding gene Chr16:14848152-14891848 (-)
NOD/ShiLtJ ENSMUSG00190043945
 protein coding gene Chr16:12409514-12453209 (-)
NOD/ShiLtJ ENSMUSG00190002620
 protein coding gene Chr6:97122614-97124474 (+)
NZO/HlLtJ ENSMUSG00225031580
 protein coding gene Chr16:18093395-18137093 (-)
PWK/PhJ ENSLUMG00010047332
 protein coding gene Chr16:12237155-12278482 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    UBE2V2, ubiquitin conjugating enzyme E2 V2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UBE2V2, ubiquitin conjugating enzyme E2 V2
  • Synonyms
    DDVit-1, DDVIT1, EDAF-1, EDPF-1, EDPF1, MMS2, UEV-2, UEV2
  • Links
    NCBI Gene ID: 7336
    UniProt: Q15819

  • Chr Location
    8q11.21; chr8:47997437-48064708 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    600
  • Tissues
    3
  • cDNA Data
    11
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70620 NCBI Gene Model | MGI Sequence Detail 43533 C57BL/6J ±  kb
transcript NM_023585 RefSeq | MGI Sequence Detail 5892 C57BL/6  
polypeptide Q9D2M8 UniProt | EBI | MGI Sequence Detail 145 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000016990 ubiquitin-conjugating enzyme E2 variant 2
    (term hierarchy)
  • InterPro Domains
    IPR016135 Ubiquitin-conjugating enzyme/RWD-like
    IPR000608 Ubiquitin-conjugating (UBC), catalytic core domain
  • GlyGen
    Q9D2M8 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 6
Other
Accession IDs
less
MGI:1919044, MGI:1925514, MGI:2146498, MGI:2146716
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:214866 JACKSON BR, et al., Recurrent carcinoma of the rectum, surgical treatment. Calif Med. 1959 Sep;91:149-50
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory