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Fbxo33 Gene Detail
Summary
  • Symbol
    Fbxo33
  • Name
    F-box protein 33
  • Synonyms
    5730501N20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917861
    NCBI Gene: 70611
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:59247441-59266511 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 26.03 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    138 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917861
 protein coding gene Chr12:59247441-59268747 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019771
 protein coding gene Chr12:58407563-58428683 (-)
A/J MGP_AJ_G0019730
 protein coding gene Chr12:56280501-56303809 (-)
AKR/J MGP_AKRJ_G0019705
 protein coding gene Chr12:58076790-58095967 (-)
BALB/cJ MGP_BALBcJ_G0019710
 protein coding gene Chr12:56662215-56685867 (-)
C3H/HeJ MGP_C3HHeJ_G0019515
 protein coding gene Chr12:58189636-58209047 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020162
 protein coding gene Chr12:60129519-60150553 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017782
 protein coding gene Chr12:54646771-54666256 (-)
CAST/EiJ MGP_CASTEiJ_G0019067
 protein coding gene Chr12:53067703-53088886 (-)
CBA/J MGP_CBAJ_G0019484
 protein coding gene Chr12:62340565-62359638 (-)
DBA/2J MGP_DBA2J_G0019600
 protein coding gene Chr12:56199377-56218449 (-)
FVB/NJ MGP_FVBNJ_G0019588
 protein coding gene Chr12:55470095-55489120 (-)
LP/J MGP_LPJ_G0019672
 protein coding gene Chr12:58439865-58460344 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019626
 protein coding gene Chr12:63931155-63952175 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020196
 protein coding gene Chr12:57512331-57531395 (-)
PWK/PhJ MGP_PWKPhJ_G0018833
 protein coding gene Chr12:50542682-50562954 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018627
 protein coding gene Chr12:51913215-51932001 (-)
WSB/EiJ MGP_WSBEiJ_G0019118
 protein coding gene Chr12:58079695-58098721 (-)



Homology
more
  • Human Ortholog
    FBXO33, F-box protein 33
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXO33, F-box protein 33
  • Synonyms
    BMND12, c14_5247, Fbx33
  • Links
    NCBI Gene ID: 254170
    neXtProt AC: NX_Q7Z6M2
    UniProt: Q7Z6M2

  • Chr Location
    14q21.1; chr14:39397684-39432466 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    1
  • cDNA Data
    57
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000035329 Ensembl Gene Model | MGI Sequence Detail 19071 C57BL/6J ±  kb
    transcript ENSMUST00000043204 Ensembl | MGI Sequence Detail 3688 Not Applicable  
    polypeptide ENSMUSP00000035948 Ensembl | MGI Sequence Detail 562 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 58
      cDNA 57
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2144868
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory