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Kcnip1 Gene Detail
Summary
  • Symbol
    Kcnip1
  • Name
    Kv channel-interacting protein 1
  • Synonyms
    2900046L02Rik, 3202002F18Rik, KCHIP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917607
    NCBI Gene: 70357
  • Alliance
    genome feature page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:33579339-33943152 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 19.21 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    10388 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917607
 protein coding gene Chr11:33579339-33943854 (-)
129S1/SvImJ ENSMUSG00200008916
 protein coding gene Chr11:30617290-30982217 (-)
A/J ENSMUSG00195013929
 protein coding gene Chr11:30524867-30890084 (-)
AKR/J ENSMUSG00220008069
 protein coding gene Chr11:30719916-31084665 (-)
BALB/cJ ENSMUSG00180007912
 protein coding gene Chr11:30551467-30923532 (-)
C3H/HeJ ENSMUSG00175015792
 protein coding gene Chr11:30531709-30896660 (-)
C57BL/6NJ ENSMUSG00215007885
 protein coding gene Chr11:30489045-30853997 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016198
 protein coding gene Chr11:29223484-29581983 (-)
CAST/EiJ ENSTCUG00005028473
 protein coding gene Chr11:30419453-30783581 (-)
CBA/J ENSMUSG00210009363
 protein coding gene Chr11:30420984-30785740 (-)
DBA/2J ENSMUSG00185018634
 protein coding gene Chr11:30610640-30975788 (-)
FVB/NJ ENSMUSG00205016692
 protein coding gene Chr11:30609336-30974144 (-)
JF1/MsJ ENSUMUG00000004320
 protein coding gene Chr11:30871815-31237642 (-)
LP/J ENSMUSG00230003748
 protein coding gene Chr11:31769308-32141272 (-)
NOD/ShiLtJ ENSMUSG00190021686
 protein coding gene Chr11:30701728-31067397 (-)
NZO/HlLtJ ENSMUSG00225030169
 protein coding gene Chr11:33667490-34032101 (-)
PWK/PhJ ENSLUMG00010016821
 protein coding gene Chr11:30527717-30894019 (-)
SPRET/EiJ ENSMSPG00010019348
 protein coding gene Chr11:30901106-31279986 (-)
WSB/EiJ ENSIUOG00005012534
 protein coding gene Chr11:30603947-30968968 (-)



Homology
more
  • Human Ortholog
    KCNIP1, potassium voltage-gated channel interacting protein 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KCNIP1, potassium voltage-gated channel interacting protein 1
  • Synonyms
    KCHIP1, VABP
  • Links
    NCBI Gene ID: 30820
    UniProt: Q9NZI2

  • Chr Location
    5q35.1; chr5:170353487-170736632 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increase susceptibility to pentylenetetrazole-induced seizures.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    50
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    878
  • Tissues
    87
  • cDNA Data
    19
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000053519 Ensembl Gene Model | MGI Sequence Detail 363814 C57BL/6J ±  kb
    transcript ENSMUST00000238436 Ensembl | MGI Sequence Detail 699 Not Applicable  
    polypeptide ENSMUSP00000158813 Ensembl | MGI Sequence Detail 232 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 27
      cDNA 23
      Primer pair 4

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1920202, MGI:2144283, MGI:2144547
    References
    more
    • Summaries
      All 54
      Developmental Gene Expression 7
      Gene Ontology 12
      Phenotypes 12
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory