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Dazap1 Gene Detail
Summary
  • Symbol
    Dazap1
  • Name
    DAZ associated protein 1
  • Synonyms
    2410042M16Rik, mPrrp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917498
    NCBI Gene: 70248
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:80097320-80124242 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    501 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917498
 protein coding gene Chr10:80097168-80124242 (+)
129S1/SvImJ ENSMUSG00200048770
 protein coding gene Chr10:76720985-76747916 (+)
A/J ENSMUSG00195040947
 protein coding gene Chr10:77116544-77143472 (+)
AKR/J ENSMUSG00220045995
 protein coding gene Chr10:76714104-76741038 (+)
BALB/cJ ENSMUSG00180048827
 protein coding gene Chr10:77127048-77153973 (+)
C3H/HeJ ENSMUSG00175052287
 protein coding gene Chr10:76997716-77024650 (+)
C57BL/6NJ ENSMUSG00215048446
 protein coding gene Chr10:76739450-76766379 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015574
 protein coding gene Chr10:74248449-74275447 (+)
CAST/EiJ ENSTCUG00005049893
 protein coding gene Chr10:76624283-76651028 (+)
CBA/J ENSMUSG00210039106
 protein coding gene Chr10:76853783-76880731 (+)
DBA/2J ENSMUSG00185044965
 protein coding gene Chr10:77196185-77223108 (+)
FVB/NJ ENSMUSG00205043895
 protein coding gene Chr10:76908965-76935896 (+)
JF1/MsJ ENSUMUG00000049236
 protein coding gene Chr10:78424834-78451494 (+)
LP/J ENSMUSG00230044493
 protein coding gene Chr10:78965920-78992844 (+)
NOD/ShiLtJ ENSMUSG00190036063
 protein coding gene Chr10:77109909-77136835 (+)
NZO/HlLtJ ENSMUSG00225049609
 protein coding gene Chr10:83252274-83279196 (+)
PWK/PhJ ENSLUMG00010036423
 protein coding gene Chr10:76786205-76813175 (+)
SPRET/EiJ ENSMSPG00010040472
 protein coding gene Chr10:78408267-78434907 (+)
WSB/EiJ ENSIUOG00005051002
 protein coding gene Chr10:76813910-76840808 (+)



Homology
more
  • Human Ortholog
    DAZAP1, DAZ associated protein 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DAZAP1, DAZ associated protein 1
  • Links
    NCBI Gene ID: 26528
    UniProt: Q96EP5

  • Chr Location
    19p13.3; chr19:1407536-1435687 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    28 phenotypes from 4 alleles in 2 genetic backgrounds
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygotes for a null allele show partial lethality during fetal growth through weaning, growth retardation, spermatogenic arrest, and premature death. Homozygotes for a hypomorphic allele live longer but are small and sterile and display small gonads, spermatogenic arrest, and abnormal pregnancy.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    35
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    747
  • Tissues
    129
  • cDNA Data
    90
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000069565 Ensembl Gene Model | MGI Sequence Detail 26923 C57BL/6J ±  kb
    transcript ENSMUST00000092305 Ensembl | MGI Sequence Detail 1994 Not Applicable  
    polypeptide ENSMUSP00000089958 Ensembl | MGI Sequence Detail 406 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 95
      cDNA 90
      Primer pair 3
      Other 2
      Antibodies 2

      Microarray probesets 3
    References
    more
    • Summaries
      All 55
      Developmental Gene Expression 3
      Gene Ontology 13
      Phenotypes 20
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory