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Ctsll3 Gene Detail
Summary
  • Symbol
    Ctsll3
  • Name
    cathepsin L-like 3
  • Synonyms
    2310051M13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917452
    NCBI Gene: 70202
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr13:60946064-60950658 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 32.53 cM, cytoband B3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    100 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917452
protein coding gene Chr13:60946064-60950663 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020650
protein coding gene Chr13:60581470-60586064 (-)
A/J MGP_AJ_G0020605
protein coding gene Chr13:58309874-58314471 (-)
AKR/J MGP_AKRJ_G0020581
protein coding gene Chr13:60039122-60043716 (-)
BALB/cJ MGP_BALBcJ_G0020601
protein coding gene Chr13:58565474-58570068 (-)
C3H/HeJ MGP_C3HHeJ_G0020398
protein coding gene Chr13:59837239-59841833 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021035
protein coding gene Chr13:62386811-62391405 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018617
protein coding gene Chr13:56174875-56179284 (-)
CAST/EiJ MGP_CASTEiJ_G0019914
protein coding gene Chr13:60063715-60068322 (-)
CBA/J MGP_CBAJ_G0020358
protein coding gene Chr13:64726633-64731227 (-)
DBA/2J MGP_DBA2J_G0020482
protein coding gene Chr13:57834847-57839441 (-)
FVB/NJ MGP_FVBNJ_G0020460
protein coding gene Chr13:57335208-57339800 (-)
LP/J MGP_LPJ_G0020558
protein coding gene Chr13:60833497-60838093 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020490
protein coding gene Chr13:63993086-63997681 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021078
protein coding gene Chr13:59646401-59650995 (-)
PWK/PhJ MGP_PWKPhJ_G0019669
protein coding gene Chr13:57885322-57890031 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019496
protein coding gene Chr13:58580617-58585230 (-)
WSB/EiJ MGP_WSBEiJ_G0019976
protein coding gene Chr13:60104127-60108721 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 70202 NCBI Gene Model | MGI Sequence Detail 4595 C57BL/6J ±  kb
transcript NM_027344 RefSeq | MGI Sequence Detail 1332 C57BL/6  
polypeptide NP_081620 RefSeq | MGI Sequence Detail 331 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR013201 Cathepsin propeptide inhibitor domain (I29)
    IPR025661 Cysteine peptidase, asparagine active site
    IPR000169 Cysteine peptidase, cysteine active site
    IPR025660 Cysteine peptidase, histidine active site
    IPR039417 Papain-like cysteine endopeptidase
    IPR038765 Papain-like cysteine peptidase superfamily
    IPR013128 Peptidase C1A
    IPR000668 Peptidase C1A, papain C-terminal
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 20
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory