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Actr1b Gene Detail
Summary
  • Symbol
    Actr1b
  • Name
    ARP1 actin-related protein 1B, centractin beta
  • Synonyms
    2310066K23Rik, Arp1b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917446
    NCBI Gene: 226977
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:36737195-36749051 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 15.38 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    477 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917446
protein coding gene Chr1:36737195-36753503 (-)
129S1/SvImJ ENSMUSG00200003820
protein coding gene Chr1:34325618-34341930 (-)
A/J ENSMUSG00195038094
protein coding gene Chr1:33946058-33962362 (-)
AKR/J ENSMUSG00220008724
protein coding gene Chr1:33967722-33984019 (-)
BALB/cJ ENSMUSG00180011037
protein coding gene Chr1:34070947-34087259 (-)
C3H/HeJ ENSMUSG00175001263
protein coding gene Chr1:33950154-33966452 (-)
C57BL/6NJ ENSMUSG00215015416
protein coding gene Chr1:34047917-34064228 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014044
protein coding gene Chr1:31352156-31369086 (-)
CAST/EiJ ENSTCUG00005002717
protein coding gene Chr1:34124528-34140792 (-)
CBA/J ENSMUSG00210005472
protein coding gene Chr1:33792984-33809255 (-)
DBA/2J ENSMUSG00185009856
protein coding gene Chr1:34877648-34893904 (-)
FVB/NJ ENSMUSG00205027509
protein coding gene Chr1:33971929-33988213 (-)
JF1/MsJ ENSUMUG00000014935
protein coding gene Chr1:34091932-34108319 (-)
LP/J ENSMUSG00230023488
protein coding gene Chr1:34946435-34962746 (-)
NOD/ShiLtJ ENSMUSG00190027197
protein coding gene Chr1:33988030-34004339 (-)
NZO/HlLtJ ENSMUSG00225013815
protein coding gene Chr1:38181051-38197331 (-)
PWK/PhJ ENSLUMG00010034024
protein coding gene Chr1:33621425-33638058 (-)
SPRET/EiJ ENSMSPG00010023240
protein coding gene Chr1:35105053-35121160 (-)
WSB/EiJ ENSIUOG00005037236
protein coding gene Chr1:33935872-33952098 (-)



Homology
more
  • Human Ortholog
    ACTR1B, actin related protein 1B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACTR1B, actin related protein 1B
  • Synonyms
    ARP1B, CTRN2, PC3
  • Links
    NCBI Gene ID: 10120
    UniProt: P42025

  • Chr Location
    2q11.2; chr2:97655939-97664114 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    5
  • Targeted
    3
  • Genomic Mutations
    1 involving Actr1b
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 226977 NCBI Gene Model | MGI Sequence Detail 11857 C57BL/6J ±  kb
transcript NM_001418139 RefSeq | MGI Sequence Detail 3355 C57BL/6  
polypeptide Q8R5C5 UniProt | EBI | MGI Sequence Detail 376 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 119
    cDNA 119

    Microarray probesets 5
Other
Accession IDs
less
MGI:2138136, MGI:2138359
References
more
  • Summaries
    All 41
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:384042 Benleulmi-Chaachoua A, et al., Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons. J Pineal Res. 2016 Jan;60(1):95-108

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/01/2026
MGI 6.24
The Jackson Laboratory