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Chn2 Gene Detail
Summary
  • Symbol
    Chn2
  • Name
    chimerin 2
  • Synonyms
    1700026N20Rik, 4930557O16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917243
    NCBI Gene: 69993
  • Alliance
    genome feature page
  • Transcription Start Sites
    22 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:54016917-54278797 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 26.54 cM, cytoband B3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    7979 from dbSNP Build 142
  • Strain Annotations
    26
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917243
 protein coding gene Chr6:54016539-54278797 (+)
129S1/SvImJ ENSMUSGG00200054693
 protein coding gene Chr6:50993323-51172614 (+)
129S1/SvImJ ENSMUSG00200005323
 protein coding gene Chr6:51218746-51255394 (+)
A/J ENSMUSG00195030561
 protein coding gene Chr6:50955810-50992463 (+)
A/J ENSMUSGG00195055454
 protein coding gene Chr6:50730467-50909601 (+)
AKR/J ENSMUSGG00220054485
 protein coding gene Chr6:50426811-50606114 (+)
AKR/J ENSMUSG00220003878
 protein coding gene Chr6:50652249-50688908 (+)
BALB/cJ ENSMUSGG00180055457
 protein coding gene Chr6:51024462-51203584 (+)
BALB/cJ ENSMUSG00180009277
 protein coding gene Chr6:51249786-51286441 (+)
C3H/HeJ ENSMUSGG00175054990
 protein coding gene Chr6:50785586-50964880 (+)
C3H/HeJ ENSMUSG00175035384
 protein coding gene Chr6:51011010-51047653 (+)
C57BL/6NJ ENSMUSGG00215055477
 protein coding gene Chr6:51000818-51179874 (+)
C57BL/6NJ ENSMUSG00215019692
 protein coding gene Chr6:51226098-51263048 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028400
 protein coding gene Chr6:48515080-48774643 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210032992
 protein coding gene Chr6:51055317-51091966 (+)
CBA/J ENSMUSGG00210054935
 protein coding gene Chr6:50829895-51009183 (+)
DBA/2J ENSMUSGG00185057664
 protein coding gene Chr6:51409549-51588816 (+)
DBA/2J ENSMUSG00185019133
 protein coding gene Chr6:51634949-51671602 (+)
FVB/NJ ENSMUSGG00205054291
 protein coding gene Chr6:51059494-51238615 (+)
FVB/NJ ENSMUSG00205019786
 protein coding gene Chr6:51284820-51321474 (+)
JF1/MsJ no annotation
LP/J ENSMUSGG00230055371
 protein coding gene Chr6:52490465-52669702 (+)
LP/J ENSMUSG00230011204
 protein coding gene Chr6:52715834-52752479 (+)
NOD/ShiLtJ ENSMUSGG00190054781
 protein coding gene Chr6:50741109-50920381 (+)
NOD/ShiLtJ ENSMUSG00190008545
 protein coding gene Chr6:50966513-51003161 (+)
NZO/HlLtJ ENSMUSG00225013212
 protein coding gene Chr6:54699508-54736202 (+)
NZO/HlLtJ ENSMUSGG00225055225
 protein coding gene Chr6:54473254-54653303 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CHN2, chimerin 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CHN2, chimerin 2
  • Synonyms
    ARHGAP3, BCH, CHN2-3, RHOGAP3
  • Links
    NCBI Gene ID: 1124
    UniProt: P52757

  • Chr Location
    7p14.3; chr7:29146547-29514334 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted allele exhibit impaired infrapyramidal tract neuron prunning.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    640
  • Tissues
    27
  • cDNA Data
    10
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69993 NCBI Gene Model | MGI Sequence Detail 261881 C57BL/6J ±  kb
transcript NM_001163640 RefSeq | MGI Sequence Detail 3150 C57BL/6  
polypeptide Q80XD1 UniProt | EBI | MGI Sequence Detail 332 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 7
Other
Accession IDs
less
MGI:1922054
References
more
  • Summaries
    All 45
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory