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Polr2i Gene Detail
Summary
  • Symbol
    Polr2i
  • Name
    polymerase (RNA) II (DNA directed) polypeptide I
  • Synonyms
    2810002B19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917170
    NCBI Gene: 69920
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:29931499-29932812 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 17.34 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    52 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917170
protein coding gene Chr7:29931373-29932815 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032007
protein coding gene Chr7:29213237-29214315 (+)
A/J MGP_AJ_G0031984
protein coding gene Chr7:28443698-28444759 (+)
AKR/J MGP_AKRJ_G0031917
protein coding gene Chr7:29171365-29172443 (+)
BALB/cJ MGP_BALBcJ_G0031991
protein coding gene Chr7:28619049-28620126 (+)
C3H/HeJ MGP_C3HHeJ_G0031710
protein coding gene Chr7:29612683-29613746 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032456
protein coding gene Chr7:30159618-30160681 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029507
protein coding gene Chr7:29479536-29480623 (+)
CAST/EiJ MGP_CASTEiJ_G0031044
protein coding gene Chr7:22866084-22867160 (+)
CBA/J MGP_CBAJ_G0031676
protein coding gene Chr7:31609845-31613841 (+)
DBA/2J MGP_DBA2J_G0031828
protein coding gene Chr7:28172418-28173495 (+)
FVB/NJ MGP_FVBNJ_G0031785
protein coding gene Chr7:28285561-28286640 (+)
LP/J MGP_LPJ_G0031909
protein coding gene Chr7:29537088-29538163 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031821
protein coding gene Chr7:30871843-30872916 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032485
protein coding gene Chr7:28668891-28669959 (+)
PWK/PhJ MGP_PWKPhJ_G0030770
protein coding gene Chr7:23204461-23205540 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030603
protein coding gene Chr7:19668644-19669711 (+)
WSB/EiJ MGP_WSBEiJ_G0031154
protein coding gene Chr7:29048824-29049898 (+)



Homology
more
  • Human Ortholog
    POLR2I, RNA polymerase II subunit I
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    POLR2I, RNA polymerase II subunit I
  • Synonyms
    hRPB14.5, RPB9
  • Links
    NCBI Gene ID: 5438
    neXtProt AC: NX_P36954
    UniProt: P36954

  • Chr Location
    19q13.12; chr19:36113709-36115213 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 69920 NCBI Gene Model | MGI Sequence Detail 1314 C57BL/6J ±  kb
transcript NM_027259 RefSeq | MGI Sequence Detail 707 Not Specified  
polypeptide P60898 UniProt | EBI | MGI Sequence Detail 125 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000012995 DNA-directed RNA polymerase II subunit RPB9
  • InterPro Domains
    IPR001529 DNA-directed RNA polymerase, M/15kDa subunit
    IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site
    IPR012164 DNA-directed RNA polymerase subunit/transcription factor S
    IPR034012 Pol II subunit B9, C-terminal zinc ribbon
    IPR001222 Zinc finger, TFIIS-type
Molecular
Reagents
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  • All nucleic 73
    cDNA 72
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 30
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:190636 Wiese CB, et al., A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory