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Rasip1 Gene Detail
Summary
  • Symbol
    Rasip1
  • Name
    Ras interacting protein 1
  • Synonyms
    2610025P08Rik, Rain
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917153
    NCBI Gene: 69903
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:45276961-45288516 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 29.39 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    314 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917153
 protein coding gene Chr7:45276912-45288517 (+)
129S1/SvImJ ENSMUSG00200025517
 protein coding gene Chr7:32874614-32886215 (+)
A/J ENSMUSG00195039503
 protein coding gene Chr7:36906787-36918415 (+)
AKR/J ENSMUSG00220008444
 protein coding gene Chr7:31206049-31217657 (+)
BALB/cJ ENSMUSG00180031944
 protein coding gene Chr7:33782182-33793810 (+)
C3H/HeJ ENSMUSG00175026171
 protein coding gene Chr7:34310537-34322137 (+)
C57BL/6NJ ENSMUSG00215037045
 protein coding gene Chr7:33569735-33581342 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029732
 protein coding gene Chr7:47566874-47578935 (+)
CAST/EiJ ENSTCUG00005042562
 protein coding gene Chr7:37312748-37324395 (+)
CBA/J ENSMUSG00210047502
 protein coding gene Chr7:34680733-34692340 (+)
DBA/2J ENSMUSG00185036425
 protein coding gene Chr7:38557355-38568955 (+)
FVB/NJ ENSMUSG00205042712
 protein coding gene Chr7:34225280-34236886 (+)
JF1/MsJ ENSUMUG00000039249
 protein coding gene Chr7:43037059-43048664 (+)
LP/J ENSMUSG00230050677
 protein coding gene Chr7:43997430-44009110 (+)
NOD/ShiLtJ ENSMUSG00190047738
 protein coding gene Chr7:34552976-34564579 (+)
NZO/HlLtJ ENSMUSG00225013236
 protein coding gene Chr7:42193790-42205396 (+)
PWK/PhJ ENSLUMG00010048612
 protein coding gene Chr7:33515083-33526747 (+)
SPRET/EiJ ENSMSPG00010030866
 protein coding gene Chr7:33285336-33296839 (+)
WSB/EiJ ENSIUOG00005020264
 protein coding gene Chr7:35100303-35111923 (+)



Homology
more
  • Human Ortholog
    RASIP1, Ras interacting protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RASIP1, Ras interacting protein 1
  • Synonyms
    RAIN
  • Links
    NCBI Gene ID: 54922
    UniProt: Q5U651

  • Chr Location
    19q13.33; chr19:48720571-48740611 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted mutation exhibit complete embryonic lethality during organogenesis associated with a failure in cardiovascular development.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    990
  • Tissues
    42
  • cDNA Data
    9
  • Literature Summary
    11
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 69903 NCBI Gene Model | MGI Sequence Detail 11556 C57BL/6J ±  kb
    transcript NM_028544 RefSeq | MGI Sequence Detail 3169 C57BL/6  
    polypeptide Q3U0S6 UniProt | EBI | MGI Sequence Detail 961 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 10
      Primer pair 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1915870, MGI:2142067
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 11
      Gene Ontology 8
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:276877 Qu X, et al., Tie2 regulates endocardial sprouting and myocardial trabeculation. JCI Insight. 2019 May 21;5
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory