About   Help   FAQ
Thap3 Gene Detail
Summary
  • Symbol
    Thap3
  • Name
    THAP domain containing, apoptosis associated protein 3
  • Synonyms
    2010013E08Rik, 2210418H06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917126
    NCBI Gene: 69876
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:152067095-152073443 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 82.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    33 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917126
 protein coding gene Chr4:152067095-152073454 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029165
 protein coding gene Chr4:156071097-156080158 (-)
A/J MGP_AJ_G0029130
 protein coding gene Chr4:149514385-149521391 (-)
AKR/J MGP_AKRJ_G0029078
 protein coding gene Chr4:153597239-153603680 (-)
BALB/cJ MGP_BALBcJ_G0029146
 protein coding gene Chr4:150001755-150008211 (-)
C3H/HeJ MGP_C3HHeJ_G0028867
 protein coding gene Chr4:154158482-154165740 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029595
 protein coding gene Chr4:161662905-161669253 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026841
 protein coding gene Chr4:141883439-141889811 (-)
CAST/EiJ MGP_CASTEiJ_G0028280
 protein coding gene Chr4:151492409-151499919 (-)
CBA/J MGP_CBAJ_G0028829
 protein coding gene Chr4:166473596-166482718 (-)
DBA/2J MGP_DBA2J_G0028978
 protein coding gene Chr4:149577198-149583556 (-)
FVB/NJ MGP_FVBNJ_G0028942
 protein coding gene Chr4:148734765-148741011 (-)
LP/J MGP_LPJ_G0029068
 protein coding gene Chr4:155993095-155999439 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028969
 protein coding gene Chr4:169520639-169527580 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029627
 protein coding gene Chr4:154129261-154135504 (-)
PWK/PhJ MGP_PWKPhJ_G0028000
 protein coding gene Chr4:145647568-145654032 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027834
 protein coding gene Chr4:148403821-148411655 (-)
WSB/EiJ MGP_WSBEiJ_G0028360
 protein coding gene Chr4:154293407-154299773 (-)



Homology
more
  • Human Ortholog
    THAP3, THAP domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    THAP3, THAP domain containing 3
  • Links
    NCBI Gene ID: 90326
    neXtProt AC: NX_Q8WTV1
    UniProt: Q8WTV1

  • Chr Location
    1p36.31; chr1:6624868-6635595 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    759
  • Tissues
    32
  • cDNA Data
    37
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69876 NCBI Gene Model | MGI Sequence Detail 6349 C57BL/6J ±  kb
transcript NM_175152 RefSeq | MGI Sequence Detail 1133 C57BL/6  
polypeptide Q8BJ25 UniProt | EBI | MGI Sequence Detail 218 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 37
    cDNA 37

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917409
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:196071 van der Weyden L, et al., Cancer of mice and men: old twists and new tails. J Pathol. 2013 May;230(1):4-16
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory