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Thap3 Gene Detail
Summary
  • Symbol
    Thap3
  • Name
    THAP domain containing, apoptosis associated protein 3
  • Synonyms
    2010013E08Rik, 2210418H06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917126
    NCBI Gene: 69876
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:152067095-152073443 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 82.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    245 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917126
 protein coding gene Chr4:152067095-152073454 (-)
129S1/SvImJ ENSMUSG00200018409
 protein coding gene Chr4:143132137-143138520 (-)
A/J ENSMUSG00195014535
 protein coding gene Chr4:144767594-144773952 (-)
AKR/J ENSMUSG00220023005
 protein coding gene Chr4:144354127-144360486 (-)
BALB/cJ ENSMUSG00180002546
 protein coding gene Chr4:142449781-142456165 (-)
C3H/HeJ ENSMUSG00175017048
 protein coding gene Chr4:145734699-145741057 (-)
C57BL/6NJ ENSMUSG00215010282
 protein coding gene Chr4:144578238-144584597 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026841
 protein coding gene Chr4:141883439-141889811 (-)
CAST/EiJ ENSTCUG00005030370
 protein coding gene Chr4:148451181-148457605 (-)
CBA/J ENSMUSG00210004490
 protein coding gene Chr4:144386328-144392686 (-)
DBA/2J ENSMUSG00185014190
 protein coding gene Chr4:147951264-147957622 (-)
FVB/NJ ENSMUSG00205011336
 protein coding gene Chr4:142847824-142854185 (-)
JF1/MsJ ENSUMUG00000004882
 protein coding gene Chr4:150967145-150973665 (-)
LP/J ENSMUSG00230019883
 protein coding gene Chr4:154684429-154690787 (-)
NOD/ShiLtJ ENSMUSG00190004038
 protein coding gene Chr4:144050476-144056834 (-)
NZO/HlLtJ ENSMUSG00225024330
 protein coding gene Chr4:158677909-158684292 (-)
PWK/PhJ ENSLUMG00010025516
 protein coding gene Chr4:143245008-143251357 (-)
SPRET/EiJ ENSMSPG00010023207
 protein coding gene Chr4:145179497-145185641 (-)
WSB/EiJ ENSIUOG00005005534
 protein coding gene Chr4:142261354-142267714 (-)



Homology
more
  • Human Ortholog
    THAP3, THAP domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    THAP3, THAP domain containing 3
  • Links
    NCBI Gene ID: 90326
    UniProt: Q8WTV1

  • Chr Location
    1p36.31; chr1:6624845-6635595 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    650
  • Tissues
    32
  • cDNA Data
    37
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69876 NCBI Gene Model | MGI Sequence Detail 6349 C57BL/6J ±  kb
transcript NM_175152 RefSeq | MGI Sequence Detail 1133 C57BL/6  
polypeptide Q8BJ25 UniProt | EBI | MGI Sequence Detail 218 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 37
    cDNA 37

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917409
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:196071 van der Weyden L, et al., Cancer of mice and men: old twists and new tails. J Pathol. 2013 May;230(1):4-16
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory