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Mb21d2 Gene Detail
Summary
  • Symbol
    Mb21d2
  • Name
    Mab-21 domain containing 2
  • Synonyms
    1600021P15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917028
    NCBI Gene: 239796
  • Alliance
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:28644928-28748425 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 16, 19.71 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3247 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917028
protein coding gene Chr16:28644928-28748802 (-)
129S1/SvImJ ENSMUSG00200036093
protein coding gene Chr16:25654870-25758375 (-)
A/J ENSMUSG00195027249
protein coding gene Chr16:25213050-25312715 (-)
AKR/J ENSMUSG00220027948
protein coding gene Chr16:25486501-25586167 (-)
BALB/cJ ENSMUSG00180025982
protein coding gene Chr16:25435053-25534720 (-)
C3H/HeJ ENSMUSG00175037155
protein coding gene Chr16:25578949-25682451 (-)
C57BL/6NJ ENSMUSG00215019257
protein coding gene Chr16:25327887-25431393 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020636
protein coding gene Chr16:25909152-26008013 (-)
CAST/EiJ ENSTCUG00005032234
protein coding gene Chr16:25876767-25976434 (-)
CBA/J ENSMUSG00210034482
protein coding gene Chr16:25621003-25724508 (-)
DBA/2J ENSMUSG00185019324
protein coding gene Chr16:25536382-25639882 (-)
FVB/NJ ENSMUSG00205013915
protein coding gene Chr16:25557494-25671464 (-)
JF1/MsJ ENSUMUG00000019968
protein coding gene Chr16:25729044-25829419 (-)
LP/J ENSMUSG00230030394
protein coding gene Chr16:28106232-28209735 (-)
NOD/ShiLtJ ENSMUSG00190028204
protein coding gene Chr16:25723557-25823199 (-)
NZO/HlLtJ ENSMUSG00225039076
protein coding gene Chr16:31344964-31444621 (-)
PWK/PhJ ENSLUMG00010028306
protein coding gene Chr16:25568701-25668376 (-)
SPRET/EiJ ENSMSPG00010018400
protein coding gene Chr16:25501831-25601168 (-)
WSB/EiJ ENSIUOG00005030931
protein coding gene Chr16:25765768-25865463 (-)



Homology
more
  • Human Ortholog
    MB21D2, Mab-21 domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MB21D2, Mab-21 domain containing 2
  • Synonyms
    C3orf59, D2A, hMB21D2
  • Links
    NCBI Gene ID: 151963
    UniProt: Q8IYB1

  • Chr Location
    3q29; chr3:192796815-192917856 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000051065 Ensembl Gene Model | MGI Sequence Detail 103498 C57BL/6J ±  kb
    transcript ENSMUST00000100023 Ensembl | MGI Sequence Detail 3055 Not Applicable  
    polypeptide ENSMUSP00000097600 Ensembl | MGI Sequence Detail 491 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 26
      cDNA 26

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2146725
    References
    more
    • Summaries
      All 34
      Gene Ontology 1
      Phenotypes 12
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.
    last database update
    09/15/2026
    MGI 6.29
    The Jackson Laboratory