Snx24 MGI Mouse Gene Detail - MGI:1916476

Symbol

Snx24
Name

sorting nexing 24
Synonyms

2810011K15Rik, 5730433I16Rik

Feature Type

protein coding gene
IDs

MGI:1916476
NCBI Gene: 69226
Alliance

genome feature page
Transcription Start Sites

15 TSS

Sequence Map

Chr18:53378734-53523992 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 18, 29.00 cM
Mapping Data

2 experiments

SNPs within 2kb

4387 from dbSNP Build 142
Strain Annotations

17

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916476	protein coding gene	Chr18:53376877-53523994 (+)
129S1/SvImJ	ENSMUSG00200031092	protein coding gene	Chr18:50417793-50561053 (+)
A/J	ENSMUSG00195004871	protein coding gene	Chr18:50578242-50721509 (+)
AKR/J	ENSMUSG00220016044	protein coding gene	Chr18:50558672-50701932 (+)
BALB/cJ	ENSMUSG00180011317	protein coding gene	Chr18:51144714-51287955 (+)
C3H/HeJ	ENSMUSG00175036020	protein coding gene	Chr18:50753757-50896989 (+)
C57BL/6NJ	ENSMUSG00215006746	protein coding gene	Chr18:50100323-50245594 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022278	protein coding gene	Chr18:50165716-50307995 (+)
CAST/EiJ	ENSTCUG00005013550	protein coding gene	Chr18:49961602-50104936 (+)
CBA/J	ENSMUSG00210031436	protein coding gene	Chr18:50681083-50824324 (+)
DBA/2J	ENSMUSG00185014528	protein coding gene	Chr18:50601138-50744382 (+)
FVB/NJ	ENSMUSG00205013077	protein coding gene	Chr18:50042729-50185988 (+)
JF1/MsJ	no annotation
LP/J	ENSMUSG00230009401	protein coding gene	Chr18:52597117-52740368 (+)
NOD/ShiLtJ	ENSMUSG00190027263	protein coding gene	Chr18:50321999-50465189 (+)
NZO/HlLtJ	ENSMUSG00225034209	protein coding gene	Chr18:52511781-52654998 (+)
PWK/PhJ	no annotation
SPRET/EiJ	ENSMSPG00010017711	protein coding gene	Chr18:51008737-51159311 (+)
WSB/EiJ	ENSIUOG00005009018	protein coding gene	Chr18:50215520-50358344 (+)

Human Ortholog

SNX24, sorting nexin 24

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SNX24, sorting nexin 24
Synonyms

PRO1284, SBBI31
Links

HGNC:21533

NCBI Gene ID: 28966

UniProt: Q9Y343
Chr Location

5q23.2; chr5:122843439-123029354 (+) GRCh38

MGI Vertebrate Homology

Snx24 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: SNX24
Gene Tree

Snx24

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Phenotype Summary

6 phenotype references

All Mutations and Alleles

6
Endonuclease-mediated

2
Gene trapped

1
Spontaneous

1
Targeted

2
Genomic Mutations

1 involving Snx24
Incidental Mutations

APF , CvDC
Find Mice (IMSR)

13 strains or lines available

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All GO Annotations

6
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

19

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase snx24

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All Sequences

42
RefSeq

9
UniProt

1
CCDS

CCDS29251.1

Ensembl

ENSMUSG00000024535 (Evidence)
NCBI Gene

69226

			Length	Strain/Species	Flank
genomic	ENSMUSG00000024535	Ensembl Gene Model \| MGI Sequence Detail	145259	C57BL/6J	± kb
transcript	ENSMUST00000165032	Ensembl \| MGI Sequence Detail	1977	Not Applicable
polypeptide	ENSMUSP00000131423	Ensembl \| MGI Sequence Detail	169	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000015373 sorting nexin-24

(term hierarchy)
InterPro Domains

IPR001683 Phox homology

IPR036871 PX domain superfamily

IPR052467 Sorting nexin PX domain-containing protein

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All nucleic 19

cDNA 19

Microarray probesets 3

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MGI:1922957, MGI:2147230

Summaries

All 31

Gene Ontology 4

Phenotypes 6
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:327181 Lewis MA, et al., Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme. BMC Biol. 2022 Mar 17;20(1):67

TSS for Snx24:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr151081	Chr18:53378650-53378679 (+)	-69 bp
Tssr151082	Chr18:53378690-53378706 (+)	-36 bp
Tssr151083	Chr18:53378710-53378731 (+)	-13 bp
Tssr151084	Chr18:53378734-53378745 (+)	6 bp
Tssr151085	Chr18:53378808-53378858 (+)	99 bp
Tssr151086	Chr18:53384002-53384006 (+)	5,270 bp
Tssr151087	Chr18:53385240-53385251 (+)	6,512 bp
Tssr151088	Chr18:53385476-53385488 (+)	6,748 bp
Tssr151091	Chr18:53409663-53409667 (+)	30,931 bp
Tssr151092	Chr18:53430374-53430390 (+)	51,648 bp
Tssr151093	Chr18:53454048-53454050 (+)	75,315 bp
Tssr151094	Chr18:53456447-53456456 (+)	77,718 bp
Tssr151095	Chr18:53474709-53474743 (+)	95,992 bp
Tssr151096	Chr18:53478308-53478312 (+)	99,576 bp
Tssr151097	Chr18:53482592-53482604 (+)	103,864 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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