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Erp27 Gene Detail
Summary
  • Symbol
    Erp27
  • Name
    endoplasmic reticulum protein 27
  • Synonyms
    1810033M07Rik, 1810047B09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916437
    NCBI Gene: 69187
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:136884309-136899178 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 66.72 cM, cytoband G1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    695 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916437
 protein coding gene Chr6:136884309-136899465 (-)
129S1/SvImJ ENSMUSG00200030664
 protein coding gene Chr6:134432779-134447964 (-)
A/J ENSMUSG00195007412
 protein coding gene Chr6:133284429-133299603 (-)
AKR/J ENSMUSG00220034467
 protein coding gene Chr6:131512510-131527686 (-)
BALB/cJ ENSMUSG00180016387
 protein coding gene Chr6:133393631-133408830 (-)
C3H/HeJ ENSMUSG00175033047
 protein coding gene Chr6:133304558-133319734 (-)
C57BL/6NJ ENSMUSG00215019733
 protein coding gene Chr6:133521252-133536128 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029004
 protein coding gene Chr6:134914950-134931771 (-)
CAST/EiJ ENSTCUG00005035257
 protein coding gene Chr6:134219459-134234823 (-)
CBA/J ENSMUSG00210003592
 protein coding gene Chr6:133356906-133372079 (-)
DBA/2J ENSMUSG00185021336
 protein coding gene Chr6:134019206-134034379 (-)
FVB/NJ ENSMUSG00205028151
 protein coding gene Chr6:132510375-132525551 (-)
JF1/MsJ ENSUMUG00000024390
 protein coding gene Chr6:132701606-132716487 (-)
LP/J ENSMUSG00230009273
 protein coding gene Chr6:135229348-135244325 (-)
NOD/ShiLtJ ENSMUSG00190006398
 protein coding gene Chr6:133857392-133872567 (-)
NZO/HlLtJ no annotation
PWK/PhJ ENSLUMG00010040628
 protein coding gene Chr6:131803925-131818812 (-)
SPRET/EiJ ENSMSPG00010033817
 protein coding gene Chr6:135704565-135720203 (-)
WSB/EiJ ENSIUOG00005019664
 protein coding gene Chr6:134174393-134189572 (-)



Homology
more
  • Human Ortholog
    ERP27, endoplasmic reticulum protein 27
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ERP27, endoplasmic reticulum protein 27
  • Synonyms
    C12orf46, PDIA8
  • Links
    NCBI Gene ID: 121506
    UniProt: Q96DN0

  • Chr Location
    12p12.3; chr12:14914039-14938537 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    617
  • Tissues
    2
  • cDNA Data
    14
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030219 Ensembl Gene Model | MGI Sequence Detail 14870 C57BL/6J ±  kb
transcript ENSMUST00000032343 Ensembl | MGI Sequence Detail 1029 Not Applicable  
polypeptide ENSMUSP00000032343 Ensembl | MGI Sequence Detail 272 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 4
Other
Accession IDs
less
MGI:1919545
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:362983 Chen F, et al., Differential transport pathways of saturated and unsaturated fatty acid esters in male mouse hepatocytes. Nat Commun. 2025 Feb 4;16(1):1344
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory