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Slx9 Gene Detail
Summary
  • Symbol
    Slx9
  • Name
    SLX9 ribosome biogenesis factor
  • Synonyms
    1810008A18Rik, Fam207a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916334
    NCBI Gene: 108707
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:77322495-77351619 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    141 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916334
 protein coding gene Chr10:77322489-77352758 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017397
 protein coding gene Chr10:77804698-77835714 (-)
A/J MGP_AJ_G0017374
 protein coding gene Chr10:75106281-75135116 (-)
AKR/J MGP_AKRJ_G0017335
 protein coding gene Chr10:77110417-77140396 (-)
BALB/cJ MGP_BALBcJ_G0017334
 protein coding gene Chr10:75300811-75330555 (-)
C3H/HeJ MGP_C3HHeJ_G0017158
 protein coding gene Chr10:77194409-77226086 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017792
 protein coding gene Chr10:80524936-80564198 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015482
 protein coding gene Chr10:71534893-71566731 (-)
CAST/EiJ MGP_CASTEiJ_G0016728
 protein coding gene Chr10:77538966-77574007 (-)
CBA/J MGP_CBAJ_G0017130
 protein coding gene Chr10:83655789-83686367 (-)
DBA/2J MGP_DBA2J_G0017235
 protein coding gene Chr10:74386743-74415370 (-)
FVB/NJ MGP_FVBNJ_G0017227
 protein coding gene Chr10:73558839-73587715 (-)
LP/J MGP_LPJ_G0017308
 protein coding gene Chr10:78277891-78311286 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017256
 protein coding gene Chr10:85687109-85719693 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017831
 protein coding gene Chr10:77187535-77220136 (-)
PWK/PhJ MGP_PWKPhJ_G0016512
 protein coding gene Chr10:74259886-74293695 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016295
 protein coding gene Chr10:76454796-76483154 (-)
WSB/EiJ MGP_WSBEiJ_G0016791
 protein coding gene Chr10:77166480-77195700 (-)



Homology
more
  • Human Ortholog
    SLX9, SLX9 ribosome biogenesis factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLX9, SLX9 ribosome biogenesis factor
  • Synonyms
    C21orf70, FAM207A, PRED56
  • Links
    NCBI Gene ID: 85395
    neXtProt AC: NX_Q9NSI2
    UniProt: Q9NSI2

  • Chr Location
    21q22.3; chr21:44939697-44976973 (+)  GRCh38
Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    37 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    17
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    7
  • Targeted
    7
  • Genomic Mutations
    4 involving Slx9
  • Find Mice (IMSR)
    22 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    772
  • Tissues
    65
  • cDNA Data
    10
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032977 Ensembl Gene Model | MGI Sequence Detail 29125 C57BL/6J ±  kb
transcript ENSMUST00000045454 Ensembl | MGI Sequence Detail 2394 Not Applicable  
polypeptide ENSMUSP00000036382 Ensembl | MGI Sequence Detail 219 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 10
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:2143559
References
more
  • Summaries
    All 61
    Developmental Gene Expression 2
    Diseases 2
    Gene Ontology 2
    Phenotypes 37
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:341136 Muza PM, et al., Cognitive impairments in a Down syndrome model with abnormal hippocampal and prefrontal dynamics and cytoarchitecture. iScience. 2023 Feb 17;26(2):106073
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory