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Zfp580 Gene Detail
Summary
  • Symbol
    Zfp580
  • Name
    zinc finger protein 580
  • Synonyms
    1500015O20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916242
    NCBI Gene: 68992
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:5054537-5056722 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 2.92 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    8 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916242
 protein coding gene Chr7:5041682-5056722 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031580
 protein coding gene Chr7:2017344-2019534 (+)
A/J MGP_AJ_G0031554
 protein coding gene Chr7:2014466-2016657 (+)
AKR/J MGP_AKRJ_G0031483
 protein coding gene Chr7:2092045-2094235 (+)
BALB/cJ MGP_BALBcJ_G0031562
 protein coding gene Chr7:2052884-2055074 (+)
C3H/HeJ MGP_C3HHeJ_G0031283
 protein coding gene Chr7:2068284-2070474 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032023
 protein coding gene Chr7:2087428-2089618 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029147
 protein coding gene Chr7:1728450-1730646 (+)
CAST/EiJ MGP_CASTEiJ_G0030647
 protein coding gene Chr7:2005121-2007309 (+)
CBA/J MGP_CBAJ_G0031241
 protein coding gene Chr7:2298557-2300747 (+)
DBA/2J MGP_DBA2J_G0031400
 protein coding gene Chr7:1984556-1986746 (+)
FVB/NJ MGP_FVBNJ_G0031352
 protein coding gene Chr7:1938817-1941007 (+)
LP/J MGP_LPJ_G0031485
 protein coding gene Chr7:2113674-2115864 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031391
 protein coding gene Chr7:2248525-2250715 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032053
 protein coding gene Chr7:1988402-1990592 (+)
PWK/PhJ MGP_PWKPhJ_G0030375
 protein coding gene Chr7:2148617-2150808 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030200
 protein coding gene Chr7:2033277-2035471 (+)
WSB/EiJ MGP_WSBEiJ_G0030742
 protein coding gene Chr7:2003953-2006146 (+)



Homology
more
  • Human Ortholog
    ZNF580, zinc finger protein 580
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF580, zinc finger protein 580
  • Links
    NCBI Gene ID: 51157
    neXtProt AC: NX_Q9UK33
    UniProt: Q9UK33

  • Chr Location
    19q13.42; chr19:55635016-55643470 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    814
  • Tissues
    76
  • cDNA Data
    16
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000055633 Ensembl Gene Model | MGI Sequence Detail 2186 C57BL/6J ±  kb
    transcript ENSMUST00000208570 Ensembl | MGI Sequence Detail 693 Not Applicable  
    polypeptide ENSMUSP00000147223 Ensembl | MGI Sequence Detail 230 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      Genomic 1
      cDNA 16

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2142036
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 5
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:338581 Hoffmann CJ, et al., Zfp580 inactivation as a new therapeutic target to enhance recovery after stroke in mice. J Cereb Blood Flow Metab. 2023 Aug;43(8):1400-1418
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory