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Snrpa1 Gene Detail
Summary
  • Symbol
    Snrpa1
  • Name
    small nuclear ribonucleoprotein polypeptide A'
  • Synonyms
    1500015N06Rik, U2 snRNP-A'
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916231
    NCBI Gene: 68981
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:65710084-65724335 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 35.47 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    483 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916231
 protein coding gene Chr7:65708751-65724335 (+)
129S1/SvImJ ENSMUSG00200011537
 protein coding gene Chr7:52424217-52441644 (+)
A/J ENSMUSG00195012956
 protein coding gene Chr7:56847382-56864808 (+)
AKR/J ENSMUSG00220019721
 protein coding gene Chr7:50349449-50366877 (+)
BALB/cJ ENSMUSG00180004500
 protein coding gene Chr7:53552727-53570136 (+)
C3H/HeJ ENSMUSG00175010658
 protein coding gene Chr7:54351220-54368645 (+)
C57BL/6NJ ENSMUSG00215014638
 protein coding gene Chr7:53484568-53501979 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029838
 protein coding gene Chr7:68801182-68816773 (+)
CAST/EiJ ENSTCUG00005012070
 protein coding gene Chr7:57027845-57045314 (+)
CBA/J ENSMUSG00210019675
 protein coding gene Chr7:54189711-54207136 (+)
DBA/2J ENSMUSG00185005890
 protein coding gene Chr7:58512683-58530436 (+)
FVB/NJ ENSMUSG00205004308
 protein coding gene Chr7:54184021-54201447 (+)
JF1/MsJ ENSUMUG00000006612
 protein coding gene Chr7:63258936-63276689 (+)
LP/J ENSMUSG00230017921
 protein coding gene Chr7:64605559-64622985 (+)
NOD/ShiLtJ ENSMUSG00190006664
 protein coding gene Chr7:54297987-54315414 (+)
NZO/HlLtJ ENSMUSG00225015645
 protein coding gene Chr7:62889829-62907252 (+)
PWK/PhJ ENSLUMG00010018713
 protein coding gene Chr7:52798514-52816250 (+)
SPRET/EiJ ENSMSPG00010003154
 protein coding gene Chr7:53186156-53201162 (+)
WSB/EiJ ENSIUOG00005004388
 protein coding gene Chr7:54735038-54750717 (+)



Homology
more
  • Human Ortholog
    SNRPA1, small nuclear ribonucleoprotein polypeptide A'
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SNRPA1, small nuclear ribonucleoprotein polypeptide A'
  • Synonyms
    Lea1, U2A'
  • Links
    NCBI Gene ID: 6627
    UniProt: P09661

  • Chr Location
    15q26.3; chr15:101281510-101295282 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SNRPA1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    43
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    815
  • Tissues
    92
  • cDNA Data
    79
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68981 NCBI Gene Model | MGI Sequence Detail 14252 C57BL/6J ±  kb
transcript NM_021336 RefSeq | MGI Sequence Detail 1250 C57BL/6  
polypeptide P57784 UniProt | EBI | MGI Sequence Detail 255 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000015340 U2 small nuclear ribonucleoprotein A'
    (term hierarchy)
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR032675 Leucine-rich repeat domain superfamily
    IPR003603 U2A'/phosphoprotein 32 family A, C-terminal
    IPR044640 U2 small nuclear ribonucleoprotein A'
  • GlyGen
    P57784 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 82
    cDNA 80
    Primer pair 2
    Antibodies 1

    Microarray probesets 5
References
more
  • Summaries
    All 46
    Developmental Gene Expression 5
    Gene Ontology 8
    Phenotypes 12
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:307963 Mrowiec K, et al., The periphilin 1-like BFAR isoform 3 is highly expressed in transcriptionally silent oocytes and involved in RNA metabolism. Biochim Biophys Acta Mol Cell Res. 2021 Sep;1868(10):119086
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory