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Ppp1r27 Gene Detail
Summary
  • Symbol
    Ppp1r27
  • Name
    protein phosphatase 1, regulatory subunit 27
  • Synonyms
    1110033I14Rik, Dysfip1, toonin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915951
    NCBI Gene: 68701
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:120440805-120441958 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 84.26 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    83 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915951
 protein coding gene Chr11:120440801-120441958 (-)
129S1/SvImJ ENSMUSG00200050702
 protein coding gene Chr11:117804202-117805355 (-)
A/J ENSMUSG00195024826
 protein coding gene Chr11:117479270-117480423 (-)
AKR/J ENSMUSG00220026572
 protein coding gene Chr11:117629676-117630829 (-)
BALB/cJ ENSMUSG00180051744
 protein coding gene Chr11:117772047-117773200 (-)
C3H/HeJ ENSMUSG00175037213
 protein coding gene Chr11:117729857-117731010 (-)
C57BL/6NJ ENSMUSG00215044660
 protein coding gene Chr11:117299784-117300937 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017526
 protein coding gene Chr11:116450889-116452040 (-)
CAST/EiJ ENSTCUG00005034485
 protein coding gene Chr11:117159389-117160541 (-)
CBA/J ENSMUSG00210047408
 protein coding gene Chr11:117443899-117445052 (-)
DBA/2J ENSMUSG00185021717
 protein coding gene Chr11:117757034-117758187 (-)
FVB/NJ ENSMUSG00205022215
 protein coding gene Chr11:117604769-117605922 (-)
JF1/MsJ ENSUMUG00000029035
 protein coding gene Chr11:118050968-118052120 (-)
LP/J ENSMUSG00230044649
 protein coding gene Chr11:118822803-118823956 (-)
NOD/ShiLtJ ENSMUSG00190043934
 protein coding gene Chr11:117828157-117829310 (-)
NZO/HlLtJ ENSMUSG00225050380
 protein coding gene Chr11:120971918-120973071 (-)
PWK/PhJ ENSLUMG00010023113
 protein coding gene Chr11:117567233-117568385 (-)
SPRET/EiJ ENSMSPG00010037549
 protein coding gene Chr11:118139569-118140720 (-)
WSB/EiJ ENSIUOG00005043046
 protein coding gene Chr11:117562626-117563779 (-)



Homology
more
  • Human Ortholog
    PPP1R27, protein phosphatase 1 regulatory subunit 27
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP1R27, protein phosphatase 1 regulatory subunit 27
  • Synonyms
    DYSFIP1
  • Links
    NCBI Gene ID: 116729
    UniProt: Q86WC6

  • Chr Location
    17q25.3; chr17:81833488-81835050 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025129 Ensembl Gene Model | MGI Sequence Detail 1154 C57BL/6J ±  kb
transcript ENSMUST00000026121 Ensembl | MGI Sequence Detail 771 Not Applicable  
polypeptide ENSMUSP00000026121 Ensembl | MGI Sequence Detail 154 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory