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Arb2a Gene Detail
Summary
  • Symbol
    Arb2a
  • Name
    ARB2 cotranscriptional regulator A
  • Synonyms
    1110033M05Rik, 2610318O14Rik, 53-E6, 9430037D06Rik, Fam172a, pEN87
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915925
    NCBI Gene: 68675
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:77856799-78314359 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 41.29 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1773 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915925
 protein coding gene Chr13:77850152-78314359 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020782
 protein coding gene Chr13:78249692-78737146 (+)
A/J MGP_AJ_G0020738
 protein coding gene Chr13:75576473-76042593 (+)
AKR/J MGP_AKRJ_G0020711
 protein coding gene Chr13:77878020-78352190 (+)
BALB/cJ MGP_BALBcJ_G0020734
 protein coding gene Chr13:76107913-76562277 (+)
C3H/HeJ MGP_C3HHeJ_G0020528
 protein coding gene Chr13:77565381-78021590 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021171
 protein coding gene Chr13:80880336-81378526 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018739
 protein coding gene Chr13:72265642-72700964 (+)
CAST/EiJ MGP_CASTEiJ_G0020046
 protein coding gene Chr13:76659758-77126230 (+)
CBA/J MGP_CBAJ_G0020487
 protein coding gene Chr13:83935634-84442370 (+)
DBA/2J MGP_DBA2J_G0020612
 protein coding gene Chr13:75293723-75740681 (+)
FVB/NJ MGP_FVBNJ_G0020592
 protein coding gene Chr13:74371553-74833672 (+)
LP/J MGP_LPJ_G0020685
 protein coding gene Chr13:78525335-79004423 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020621
 protein coding gene Chr13:82380498-82908083 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021211
 protein coding gene Chr13:77208608-77689134 (+)
PWK/PhJ MGP_PWKPhJ_G0019799
 protein coding gene Chr13:74184088-74636623 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019622
 protein coding gene Chr13:73513823-73958960 (+)
WSB/EiJ MGP_WSBEiJ_G0020103
 protein coding gene Chr13:77696716-78145701 (+)



Homology
more
  • Human Ortholog
    ARB2A, ARB2 cotranscriptional regulator A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARB2A, ARB2 cotranscriptional regulator A
  • Synonyms
    C5orf21, FAM172A, Toupee
  • Links
    NCBI Gene ID: 83989
    neXtProt AC: NX_Q8WUF8
    UniProt: Q8WUF8

  • Chr Location
    5q15; chr5:93617725-94111699 (-)  GRCh38
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    41 phenotypes from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    1
  • cDNA Data
    12
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68675 NCBI Gene Model | MGI Sequence Detail 457561 C57BL/6J ±  kb
    transcript NM_138312 RefSeq | MGI Sequence Detail 4036 C57BL/6  
    polypeptide Q3TNH5 UniProt | EBI | MGI Sequence Detail 417 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 14

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1919788, MGI:2176345, MGI:2442300
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 4
      Phenotypes 13
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:329885 Belanger C, et al., CHARGE syndrome-associated proteins FAM172A and CHD7 influence male sex determination and differentiation through transcriptional and alternative splicing mechanisms. FASEB J. 2022 Mar;36(3):e22176
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory