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Zfyve21 Gene Detail
Summary
  • Symbol
    Zfyve21
  • Name
    zinc finger, FYVE domain containing 21
  • Synonyms
    1110013H04Rik, C85416
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915770
    NCBI Gene: 68520
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:111780600-111794822 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 61.14 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    212 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915770
 protein coding gene Chr12:111780600-111798626 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020143
 protein coding gene Chr12:114234488-114248738 (+)
A/J MGP_AJ_G0020099
 protein coding gene Chr12:109842394-109858343 (+)
AKR/J MGP_AKRJ_G0020074
 protein coding gene Chr12:112990668-113006615 (+)
BALB/cJ MGP_BALBcJ_G0020084
 protein coding gene Chr12:110261872-110276693 (+)
C3H/HeJ MGP_C3HHeJ_G0019886
 protein coding gene Chr12:113490076-113506021 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020529
 protein coding gene Chr12:117782730-117796975 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018142
 protein coding gene Chr12:106275158-106291251 (+)
CAST/EiJ MGP_CASTEiJ_G0019427
 protein coding gene Chr12:108341996-108357854 (+)
CBA/J MGP_CBAJ_G0019853
 protein coding gene Chr12:122280208-122296154 (+)
DBA/2J MGP_DBA2J_G0019970
 protein coding gene Chr12:109317780-109333728 (+)
FVB/NJ MGP_FVBNJ_G0019955
 protein coding gene Chr12:108126352-108142298 (+)
LP/J MGP_LPJ_G0020045
 protein coding gene Chr12:114062946-114080162 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019993
 protein coding gene Chr12:125386681-125401093 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020558
 protein coding gene Chr12:112513039-112528991 (+)
PWK/PhJ MGP_PWKPhJ_G0019188
 protein coding gene Chr12:103965740-103981857 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018991
 protein coding gene Chr12:106675526-106691428 (+)
WSB/EiJ MGP_WSBEiJ_G0019486
 protein coding gene Chr12:113419276-113435255 (+)



Homology
more
  • Human Ortholog
    ZFYVE21, zinc finger FYVE-type containing 21
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZFYVE21, zinc finger FYVE-type containing 21
  • Synonyms
    HCVP7TP1, ZF21
  • Links
    NCBI Gene ID: 79038
    neXtProt AC: NX_Q9BQ24
    UniProt: Q9BQ24

  • Chr Location
    14q32.33; chr14:103715730-103733668 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    769
  • Tissues
    45
  • cDNA Data
    60
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68520 NCBI Gene Model | MGI Sequence Detail 14223 C57BL/6J ±  kb
transcript NM_026752 RefSeq | MGI Sequence Detail 1310 C57BL/6  
polypeptide Q8VCM3 UniProt | EBI | MGI Sequence Detail 234 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 61
    cDNA 61

    Microarray probesets 4
Other
Accession IDs
less
MGI:2145050, MGI:2145117
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory