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Mob1b Gene Detail
Summary
  • Symbol
    Mob1b
  • Name
    MOB kinase activator 1B
  • Synonyms
    1110003E08Rik, Mobkl1a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915723
    NCBI Gene: 68473
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:88868730-88906314 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 43.92 cM, cytoband E2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    761 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915723
 protein coding gene Chr5:88868714-88912079 (+)
129S1/SvImJ ENSMUSG00200007799
 protein coding gene Chr5:84597399-84640771 (+)
A/J ENSMUSG00195025182
 protein coding gene Chr5:83770190-83813564 (+)
AKR/J ENSMUSG00220010987
 protein coding gene Chr5:83913472-83956841 (+)
BALB/cJ ENSMUSG00180023956
 protein coding gene Chr5:83597146-83640497 (+)
C3H/HeJ ENSMUSG00175039477
 protein coding gene Chr5:85688948-85732296 (+)
C57BL/6NJ ENSMUSG00215029053
 protein coding gene Chr5:84463226-84506592 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027378
 protein coding gene Chr5:81993929-82038997 (+)
CAST/EiJ ENSTCUG00005033152
 protein coding gene Chr5:83398585-83442674 (+)
CBA/J ENSMUSG00210005865
 protein coding gene Chr5:84492361-84535722 (+)
DBA/2J ENSMUSG00185038904
 protein coding gene Chr5:86406773-86450132 (+)
FVB/NJ ENSMUSG00205016487
 protein coding gene Chr5:83305557-83348927 (+)
JF1/MsJ ENSUMUG00000000505
 protein coding gene Chr5:90763784-90808046 (+)
LP/J ENSMUSG00230024355
 protein coding gene Chr5:91123901-91167271 (+)
NOD/ShiLtJ ENSMUSG00190028195
 protein coding gene Chr5:83360674-83404032 (+)
NZO/HlLtJ ENSMUSGG00225055322
 protein coding gene Chr5:96264701-96303483 (+)
PWK/PhJ ENSLUMG00010028465
 protein coding gene Chr5:83424704-83468785 (+)
SPRET/EiJ ENSMSPG00010035239
 protein coding gene Chr5:85836824-85880362 (+)
WSB/EiJ ENSIUOG00005026144
 protein coding gene Chr5:86389276-86432657 (+)



Homology
more
  • Human Ortholog
    MOB1B, MOB kinase activator 1B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MOB1B, MOB kinase activator 1B
  • Synonyms
    MATS2, MOB4A, MOBKL1A
  • Links
    NCBI Gene ID: 92597
    UniProt: Q7L9L4

  • Chr Location
    4q13.3; chr4:70901851-71022449 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    51 phenotypes from multigenic genotypes
    6 images
    23 phenotype references
  • All Mutations and Alleles
    22
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    6
  • Gene trapped
    9
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Mob1b
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    19 strains or lines available
Mice homozygous for a gene trap allele exhibit no abnormal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    19
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 68473 NCBI Gene Model | MGI Sequence Detail 37585 C57BL/6J ±  kb
transcript NM_026735 RefSeq | MGI Sequence Detail 3171 C57BL/6  
polypeptide Q8BPB0 UniProt | EBI | MGI Sequence Detail 216 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 19

    Microarray probesets 6
Other
Accession IDs
less
MGI:2141027
References
more
  • Summaries
    All 59
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 23
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:370106 Pan Y, et al., Mesenchymal SLMAP coordinates with MST3 to govern gut elongation during development. Development. 2025 Oct 15;152(20):dev204483
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory