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Mtus2 Gene Detail
Summary
  • Symbol
    Mtus2
  • Name
    microtubule associated tumor suppressor candidate 2
  • Synonyms
    5730592G18Rik, A730013O20Rik, C130038G02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915388
    NCBI Gene: 77521
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:147894130-148252875 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 87.82 cM, cytoband G3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    13633 from dbSNP Build 142
  • Strain Annotations
    36
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915388
 protein coding gene Chr5:147894085-148252875 (+)
129S1/SvImJ ENSMUSGG00200054864
 protein coding gene Chr5:142036589-142060388 (+)
129S1/SvImJ ENSMUSG00200041568
 protein coding gene Chr5:142074463-142085299 (+)
129S1/SvImJ ENSMUSGG00200054504
 protein coding gene Chr5:141848795-141849152 (+)
A/J ENSMUSG00195040724
 protein coding gene Chr5:141665614-141676450 (+)
A/J ENSMUSGG00195054967
 protein coding gene Chr5:141627728-141651527 (+)
A/J ENSMUSGG00195055098
 protein coding gene Chr5:141433255-141433612 (+)
AKR/J ENSMUSGG00220054326
 protein coding gene Chr5:140457111-140457468 (+)
AKR/J ENSMUSGG00220054325
 protein coding gene Chr5:140644800-140668586 (+)
BALB/cJ ENSMUSG00180032175
 protein coding gene Chr5:142067959-142078793 (+)
BALB/cJ ENSMUSGG00180055055
 protein coding gene Chr5:142030078-142053878 (+)
BALB/cJ ENSMUSGG00180055214
 protein coding gene Chr5:141835621-141835978 (+)
C3H/HeJ ENSMUSGG00175054939
 protein coding gene Chr5:143676535-143676892 (+)
C3H/HeJ ENSMUSGG00175054942
 protein coding gene Chr5:143871003-143894805 (+)
C3H/HeJ ENSMUSG00175010650
 protein coding gene Chr5:143908886-143919720 (+)
C57BL/6NJ ENSMUSGG00215055287
 protein coding gene Chr5:141402905-141403262 (+)
C57BL/6NJ ENSMUSGG00215055286
 protein coding gene Chr5:141592054-141615851 (+)
C57BL/6NJ ENSMUSG00215035237
 protein coding gene Chr5:141629928-141640762 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028044
 protein coding gene Chr5:141540786-141889723 (+)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210054917
 protein coding gene Chr5:142593430-142593787 (+)
CBA/J ENSMUSGG00210054974
 protein coding gene Chr5:142782564-142806363 (+)
CBA/J ENSMUSG00210000433
 protein coding gene Chr5:142820440-142831271 (+)
DBA/2J ENSMUSG00185036111
 protein coding gene Chr5:145790313-145801146 (+)
DBA/2J ENSMUSGG00185057640
 protein coding gene Chr5:145563305-145563662 (+)
DBA/2J ENSMUSGG00185057641
 protein coding gene Chr5:145752437-145776236 (+)
FVB/NJ ENSMUSGG00205054550
 protein coding gene Chr5:141402725-141433848 (+)
FVB/NJ ENSMUSGG00205054161
 protein coding gene Chr5:141210186-141210543 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230028487
 protein coding gene Chr5:149791246-149802082 (+)
LP/J ENSMUSGG00230055482
 protein coding gene Chr5:149753373-149777171 (+)
LP/J ENSMUSGG00230055819
 protein coding gene Chr5:149565621-149565978 (+)
NOD/ShiLtJ ENSMUSGG00190054655
 protein coding gene Chr5:141206292-141206649 (+)
NOD/ShiLtJ ENSMUSGG00190054654
 protein coding gene Chr5:141393901-141417690 (+)
NZO/HlLtJ ENSMUSGG00225055374
 protein coding gene Chr5:157498350-157522145 (+)
NZO/HlLtJ ENSMUSG00225007779
 protein coding gene Chr5:157536222-157547055 (+)
NZO/HlLtJ ENSMUSGG00225055373
 protein coding gene Chr5:157309242-157309599 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010005978
 protein coding gene Chr5:143104866-143342815 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    MTUS2, microtubule associated scaffold protein 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MTUS2, microtubule associated scaffold protein 2
  • Synonyms
    CAZIP, ICIS, KIAA0774, TIP150
  • Links
    NCBI Gene ID: 23281
    UniProt: Q5JR59

  • Chr Location
    13q12.3; chr13:28819963-29505947 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    863
  • Tissues
    111
  • cDNA Data
    27
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029651 Ensembl Gene Model | MGI Sequence Detail 358746 C57BL/6J ±  kb
transcript ENSMUST00000085558 Ensembl | MGI Sequence Detail 7543 Not Applicable  
polypeptide ENSMUSP00000082694 Ensembl | MGI Sequence Detail 1353 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000030237 microtubule-associated tumor suppressor candidate 2
    (term hierarchy)
  • InterPro Domains
    IPR051293 Microtubule-associated tumor suppressor/Coiled-coil domain-containing protein 69
    IPR060408 MTUS1/CCDC69, second coiled-coil domain
  • GlyGen
    Q3UHD3 3 sites, 2 N-linked glycans (3 sites)
Molecular
Reagents
less
  • All nucleic 35
    Genomic 1
    cDNA 28
    Primer pair 4
    Other 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:1924771, MGI:2141097, MGI:2685609
References
more
  • Summaries
    All 35
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory