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Cfap298 Gene Detail
Summary
  • Symbol
    Cfap298
  • Name
    cilia and flagella associate protien 298
  • Synonyms
    1110004E09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915251
    NCBI Gene: 68001
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:90722697-90732002 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 52.17 cM, cytoband C3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    351 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915251
 protein coding gene Chr16:90721178-90732002 (-)
129S1/SvImJ ENSMUSG00200036793
 protein coding gene Chr16:87631535-87640834 (-)
A/J ENSMUSG00195027776
 protein coding gene Chr16:87408370-87417676 (-)
AKR/J ENSMUSG00220015775
 protein coding gene Chr16:87598518-87607817 (-)
BALB/cJ ENSMUSG00180013687
 protein coding gene Chr16:87481714-87491021 (-)
C3H/HeJ ENSMUSG00175015443
 protein coding gene Chr16:87819361-87828667 (-)
C57BL/6NJ ENSMUSG00215030093
 protein coding gene Chr16:87609267-87618572 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020950
 protein coding gene Chr16:85315900-85325925 (-)
CAST/EiJ ENSTCUG00005018615
 protein coding gene Chr16:87150517-87159823 (-)
CBA/J ENSMUSG00210032205
 protein coding gene Chr16:87709790-87719131 (-)
DBA/2J ENSMUSG00185033536
 protein coding gene Chr16:87667826-87677166 (-)
FVB/NJ ENSMUSG00205022958
 protein coding gene Chr16:87438220-87447476 (-)
JF1/MsJ ENSUMUG00000033255
 protein coding gene Chr16:87797729-87807065 (-)
LP/J ENSMUSG00230033295
 protein coding gene Chr16:90177039-90186338 (-)
NOD/ShiLtJ ENSMUSG00190022222
 protein coding gene Chr16:87640010-87649264 (-)
NZO/HlLtJ ENSMUSG00225030382
 protein coding gene Chr16:93313124-93322378 (-)
PWK/PhJ ENSLUMG00010011732
 protein coding gene Chr16:87433196-87442532 (-)
SPRET/EiJ ENSMSPG00010027884
 protein coding gene Chr16:88581063-88590298 (-)
WSB/EiJ ENSIUOG00005018230
 protein coding gene Chr16:87547938-87557218 (-)



Homology
more
  • Human Ortholog
    CFAP298, cilia and flagella associated protein 298
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CFAP298, cilia and flagella associated protein 298
  • Synonyms
    C21orf48, C21orf59, CILD26, DNAAF16, FBB18, Kur
  • Links
    NCBI Gene ID: 56683
    UniProt: P57076

  • Chr Location
    21q22.11; chr21:32592079-32612845 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CFAP298 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    4 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    78 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    7
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    755
  • Tissues
    70
  • cDNA Data
    43
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022972 Ensembl Gene Model | MGI Sequence Detail 9306 C57BL/6J ±  kb
transcript ENSMUST00000023694 Ensembl | MGI Sequence Detail 1430 Not Applicable  
polypeptide ENSMUSP00000023694 Ensembl | MGI Sequence Detail 290 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR021298 Cilia- and flagella-associated protein 298
Molecular
Reagents
less
  • All nucleic 46
    cDNA 44
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:6156330
References
more
  • Summaries
    All 106
    Developmental Gene Expression 3
    Diseases 4
    Gene Ontology 7
    Phenotypes 78
  • Earliest
    J:42265 Huang TT, et al., Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Arch Biochem Biophys. 1997 Aug 15;344(2):424-32
  • Latest
    J:385727 Harada K, et al., Preventing Differentiation Towards Primitive Macrophages in Stem Cells With Down Syndrome. Immunology. 2026 Mar;177(3):596-612
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory