About   Help   FAQ
Wdr55 Gene Detail
Summary
  • Symbol
    Wdr55
  • Name
    WD repeat domain 55
  • Synonyms
    2410080P20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915186
    NCBI Gene: 67936
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:36893275-36896761 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 19.46 cM, cytoband B3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    36 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915186
 protein coding gene Chr18:36893273-36896863 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024289
 protein coding gene Chr18:35173288-35176763 (+)
A/J MGP_AJ_G0024255
 protein coding gene Chr18:33934278-33937753 (+)
AKR/J MGP_AKRJ_G0024223
 protein coding gene Chr18:34889327-34892802 (+)
BALB/cJ MGP_BALBcJ_G0024255
 protein coding gene Chr18:33983421-33986896 (+)
C3H/HeJ MGP_C3HHeJ_G0024022
 protein coding gene Chr18:34953246-34956721 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024696
 protein coding gene Chr18:36409935-36413404 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022136
 protein coding gene Chr18:34027852-34031653 (+)
CAST/EiJ MGP_CASTEiJ_G0023497
 protein coding gene Chr18:34968100-34971585 (+)
CBA/J MGP_CBAJ_G0023990
 protein coding gene Chr18:37487537-37491012 (+)
DBA/2J MGP_DBA2J_G0024122
 protein coding gene Chr18:33551403-33554878 (+)
FVB/NJ MGP_FVBNJ_G0024089
 protein coding gene Chr18:33261053-33264528 (+)
LP/J MGP_LPJ_G0024204
 protein coding gene Chr18:35207501-35210976 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024117
 protein coding gene Chr18:38701622-38705097 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024745
 protein coding gene Chr18:34759718-34763193 (+)
PWK/PhJ MGP_PWKPhJ_G0023241
 protein coding gene Chr18:33812611-33816094 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023048
 protein coding gene Chr18:35012171-35015614 (+)
WSB/EiJ MGP_WSBEiJ_G0023560
 protein coding gene Chr18:34679439-34682913 (+)



Homology
more
  • Human Ortholog
    WDR55, WD repeat domain 55
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR55, WD repeat domain 55
  • Links
    NCBI Gene ID: 54853
    neXtProt AC: NX_Q9H6Y2
    UniProt: Q9H6Y2

  • Chr Location
    5q31.3; chr5:140664868-140674124 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice display embryonic lethality.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    2
  • cDNA Data
    60
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67936 NCBI Gene Model | MGI Sequence Detail 3487 C57BL/6J ±  kb
transcript NR_154585 RefSeq | MGI Sequence Detail 1525 C57BL/6  
polypeptide Q9CX97 UniProt | EBI | MGI Sequence Detail 388 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 61
    cDNA 60
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147409
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory