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Cfap410 Gene Detail
Summary
  • Symbol
    Cfap410
  • Name
    cilia and flagella associated protein 410
  • Synonyms
    1810043G02Rik, D10Jhu13e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915134
    NCBI Gene: 67884
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:77814364-77821272 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    257 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915134
 protein coding gene Chr10:77814358-77822739 (+)
129S1/SvImJ ENSMUSG00200041141
 protein coding gene Chr10:74492329-74500714 (+)
A/J ENSMUSG00195043878
 protein coding gene Chr10:74829079-74837462 (+)
AKR/J ENSMUSG00220045149
 protein coding gene Chr10:74488651-74497034 (+)
BALB/cJ ENSMUSG00180047654
 protein coding gene Chr10:74843443-74851826 (+)
C3H/HeJ ENSMUSG00175040891
 protein coding gene Chr10:74714581-74722964 (+)
C57BL/6NJ ENSMUSG00215052748
 protein coding gene Chr10:74452339-74460723 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015499
 protein coding gene Chr10:72023888-72032254 (+)
CAST/EiJ ENSTCUG00005045650
 protein coding gene Chr10:74334257-74342632 (+)
CBA/J ENSMUSG00210039066
 protein coding gene Chr10:74570721-74579103 (+)
DBA/2J ENSMUSG00185046009
 protein coding gene Chr10:74913051-74921434 (+)
FVB/NJ ENSMUSG00205048549
 protein coding gene Chr10:74605082-74613466 (+)
JF1/MsJ ENSUMUG00000054391
 protein coding gene Chr10:76074853-76083237 (+)
LP/J ENSMUSG00230047605
 protein coding gene Chr10:76682558-76690940 (+)
NOD/ShiLtJ ENSMUSG00190049954
 protein coding gene Chr10:74890525-74898907 (+)
NZO/HlLtJ ENSMUSG00225044952
 protein coding gene Chr10:80970339-80978720 (+)
PWK/PhJ ENSLUMG00010036846
 protein coding gene Chr10:74458693-74468532 (+)
SPRET/EiJ ENSMSPG00010045289
 protein coding gene Chr10:76243625-76250601 (+)
WSB/EiJ ENSIUOG00005048254
 protein coding gene Chr10:74490746-74499122 (+)



Homology
more
  • Human Ortholog
    CFAP410, cilia and flagella associated protein 410
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CFAP410, cilia and flagella associated protein 410
  • Synonyms
    C21orf2, LRRC76, RDMS, SMDAX, YF5/A2
  • Links
    NCBI Gene ID: 755
    UniProt: O43822

  • Chr Location
    21q22.3; chr21:44328944-44339402 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CFAP410 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    40 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    9
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    817
  • Tissues
    176
  • cDNA Data
    36
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67884 NCBI Gene Model | MGI Sequence Detail 6909 C57BL/6J ±  kb
transcript NM_026431 RefSeq | MGI Sequence Detail 1696 ZRU/MplStud  
polypeptide Q8C6G1 UniProt | EBI | MGI Sequence Detail 249 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 58
    Genomic 16
    cDNA 38
    Primer pair 4

    Microarray probesets 5
Other
Accession IDs
less
MGI:1336160, MGI:2143776, MGI:6285793
References
more
  • Summaries
    All 79
    Developmental Gene Expression 5
    Diseases 2
    Gene Ontology 9
    Phenotypes 40
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:372425 Ferguson R, et al., Functional variants of CFAP410 affect the DNA damage response leading to motor neuron degeneration - Implications for ALS. iScience. 2025 Sep 19;28(9):113338
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory