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Dnajb11 Gene Detail
Summary
  • Symbol
    Dnajb11
  • Name
    DnaJ heat shock protein family (Hsp40) member B11
  • Synonyms
    1810031F23Rik, ABBP-2, Dj9, ERdj3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915088
    NCBI Gene: 67838
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:22676595-22698384 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 13.71 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    771 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915088
 protein coding gene Chr16:22676595-22698384 (+)
129S1/SvImJ ENSMUSG00200043785
 protein coding gene Chr16:19676490-19698280 (+)
A/J ENSMUSG00195029727
 protein coding gene Chr16:19234831-19256622 (+)
AKR/J ENSMUSG00220041012
 protein coding gene Chr16:19554244-19576034 (+)
BALB/cJ ENSMUSG00180035610
 protein coding gene Chr16:19475419-19497211 (+)
C3H/HeJ ENSMUSG00175045488
 protein coding gene Chr16:19620357-19642147 (+)
C57BL/6NJ ENSMUSG00215039245
 protein coding gene Chr16:19347568-19369357 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020607
 protein coding gene Chr16:20090731-20112649 (+)
CAST/EiJ ENSTCUG00005043500
 protein coding gene Chr16:19962531-19984260 (+)
CBA/J ENSMUSG00210038562
 protein coding gene Chr16:19642070-19663859 (+)
DBA/2J ENSMUSG00185028547
 protein coding gene Chr16:19580822-19602612 (+)
FVB/NJ ENSMUSG00205022873
 protein coding gene Chr16:19576754-19598544 (+)
JF1/MsJ ENSUMUG00000044767
 protein coding gene Chr16:19809084-19830813 (+)
LP/J ENSMUSG00230032713
 protein coding gene Chr16:22159903-22181693 (+)
NOD/ShiLtJ ENSMUSG00190031606
 protein coding gene Chr16:19722281-19744070 (+)
NZO/HlLtJ ENSMUSG00225036135
 protein coding gene Chr16:25411001-25432791 (+)
PWK/PhJ ENSLUMG00010041516
 protein coding gene Chr16:19632281-19654049 (+)
SPRET/EiJ ENSMSPG00010035564
 protein coding gene Chr16:19509300-19523861 (+)
WSB/EiJ ENSIUOG00005038541
 protein coding gene Chr16:19825616-19847367 (+)



Homology
more
  • Human Ortholog
    DNAJB11, DnaJ heat shock protein family (Hsp40) member B11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DNAJB11, DnaJ heat shock protein family (Hsp40) member B11
  • Synonyms
    ABBP-2, ABBP2, Dj-9, DJ9, EDJ, ERdj3, ERj3, ERj3p, PKD6, PRO1080, UNQ537
  • Links
    NCBI Gene ID: 51726
    UniProt: Q9UBS4

  • Chr Location
    3q27.3; chr3:186567403-186585800 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human DNAJB11 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    1
  • cDNA Data
    13
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67838 NCBI Gene Model | MGI Sequence Detail 21790 C57BL/6J ±  kb
    transcript NM_026400 RefSeq | MGI Sequence Detail 2534 C57BL/6  
    polypeptide Q99KV1 UniProt | EBI | MGI Sequence Detail 358 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 13
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2146528
    References
    more
    • Summaries
      All 56
      Developmental Gene Expression 4
      Gene Ontology 11
      Phenotypes 13
    • Earliest
      J:63971 Yu M, et al., HEDJ, an Hsp40 co-chaperone localized to the endoplasmic reticulum of human cells. J Biol Chem. 2000 Aug 11;275(32):24984-92
    • Latest
      J:375699 Busch T, et al., SDF2 and SDF2L1 are essential co-factors of DNAJB11 for Polycystin-1 processing. J Biol Chem. 2025 Oct 16;301(12):110823
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory