About   Help   FAQ
Wdr83 Gene Detail
Summary
  • Symbol
    Wdr83
  • Name
    WD repeat domain containing 83
  • Synonyms
    1500041N16Rik, Morg1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915086
    NCBI Gene: 67836
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:85801664-85807375 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 41.55 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    185 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915086
 protein coding gene Chr8:85801664-85807935 (-)
129S1/SvImJ ENSMUSG00200024559
 protein coding gene Chr8:80165400-80173674 (-)
A/J ENSMUSG00195015049
 protein coding gene Chr8:80523427-80531708 (-)
AKR/J ENSMUSG00220022861
 protein coding gene Chr8:80565027-80573302 (-)
BALB/cJ ENSMUSG00180020063
 protein coding gene Chr8:80364129-80372404 (-)
C3H/HeJ ENSMUSG00175024611
 protein coding gene Chr8:80459103-80467384 (-)
C57BL/6NJ ENSMUSG00215010720
 protein coding gene Chr8:80097020-80104250 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031330
 protein coding gene Chr8:76426844-76433093 (-)
CAST/EiJ ENSTCUG00005036409
 protein coding gene Chr8:79973543-79980755 (-)
CBA/J ENSMUSG00210030750
 protein coding gene Chr8:80446227-80454508 (-)
DBA/2J ENSMUSG00185037393
 protein coding gene Chr8:86554815-86563096 (-)
FVB/NJ ENSMUSG00205035341
 protein coding gene Chr8:79502081-79510362 (-)
JF1/MsJ ENSUMUG00000020781
 protein coding gene Chr8:88863673-88870883 (-)
LP/J ENSMUSG00230024658
 protein coding gene Chr8:90162383-90170657 (-)
NOD/ShiLtJ ENSMUSG00190015184
 protein coding gene Chr8:80522540-80530821 (-)
NZO/HlLtJ ENSMUSG00225040317
 protein coding gene Chr8:93557708-93564982 (-)
PWK/PhJ ENSLUMG00010028288
 protein coding gene Chr8:80200667-80207888 (-)
SPRET/EiJ ENSMSPG00010025608
 protein coding gene Chr8:82113130-82121087 (-)
WSB/EiJ ENSIUOG00005018363
 protein coding gene Chr8:81260160-81268435 (-)



Homology
more
  • Human Ortholog
    WDR83, WD repeat domain 83
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR83, WD repeat domain 83
  • Synonyms
    MORG1
  • Links
    NCBI Gene ID: 84292
    UniProt: Q9BRX9

  • Chr Location
    19p13.13; chr19:12666802-12675832 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    41 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a reporter allele exhibit embryonic lethality at E10.5 due to diffuse vascularization and placental insufficiency. Mice heterozygous for the same reporter allele exhibit decreased susceptibility to kidney reperfusion injury.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    11
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    649
  • Tissues
    42
  • cDNA Data
    47
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67836 NCBI Gene Model | MGI Sequence Detail 5712 C57BL/6J ±  kb
    transcript NM_026399 RefSeq | MGI Sequence Detail 1238 Not Specified  
    polypeptide Q9DAJ4 UniProt | EBI | MGI Sequence Detail 315 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 47
      cDNA 47
      Antibodies 3

      Microarray probesets 3
    References
    more
    • Summaries
      All 73
      Developmental Gene Expression 3
      Gene Ontology 11
      Phenotypes 41
    • Earliest
      J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
    • Latest
      J:378046 Tabata H, et al., The p.L218P variant in WDR83 disrupts neuronal development, leading to neurodevelopmental disorder. Sci Rep. 2025 Dec 11;16(1):2213
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory