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Hapln3 Gene Detail
Summary
  • Symbol
    Hapln3
  • Name
    hyaluronan and proteoglycan link protein 3
  • Synonyms
    4930554N11Rik, Lpr3
Location &
Maps
more
  • Sequence Map
    Chr7:78764850-78780766 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 44.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    525 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914916
 protein coding gene Chr7:78764850-78783100 (-)
129S1/SvImJ ENSMUSG00200034325
 protein coding gene Chr7:65582511-65598218 (-)
A/J ENSMUSG00195013948
 protein coding gene Chr7:69998854-70014479 (-)
AKR/J ENSMUSG00220034674
 protein coding gene Chr7:63540869-63556498 (-)
BALB/cJ ENSMUSG00180013019
 protein coding gene Chr7:66723984-66739608 (-)
C3H/HeJ ENSMUSG00175020615
 protein coding gene Chr7:67494600-67510305 (-)
C57BL/6NJ ENSMUSG00215012477
 protein coding gene Chr7:66589246-66605226 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029875
 protein coding gene Chr7:81668593-81683707 (-)
CAST/EiJ ENSTCUG00005004080
 protein coding gene Chr7:70047205-70062831 (-)
CBA/J ENSMUSG00210023908
 protein coding gene Chr7:67345909-67361613 (-)
DBA/2J ENSMUSG00185044204
 protein coding gene Chr7:71668613-71684320 (-)
FVB/NJ ENSMUSG00205017545
 protein coding gene Chr7:67228125-67243817 (-)
JF1/MsJ ENSUMUG00000023847
 protein coding gene Chr7:76324766-76340418 (-)
LP/J ENSMUSG00230014178
 protein coding gene Chr7:77759687-77775373 (-)
NOD/ShiLtJ ENSMUSG00190018055
 protein coding gene Chr7:67488579-67504259 (-)
NZO/HlLtJ ENSMUSG00225042105
 protein coding gene Chr7:76000337-76015988 (-)
PWK/PhJ ENSLUMG00010016282
 protein coding gene Chr7:65916569-65932157 (-)
SPRET/EiJ ENSMSPG00010021230
 protein coding gene Chr7:66335014-66350619 (-)
WSB/EiJ ENSIUOG00005019871
 protein coding gene Chr7:67838631-67854299 (-)



Homology
more
  • Human Ortholog
    HAPLN3, hyaluronan and proteoglycan link protein 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HAPLN3, hyaluronan and proteoglycan link protein 3
  • Synonyms
    EXLD1, HsT19883
  • Links
    NCBI Gene ID: 145864
    UniProt: Q96S86

  • Chr Location
    15q26.1; chr15:88877294-88895597 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    4
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    3 involving Hapln3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    25 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030606 Ensembl Gene Model | MGI Sequence Detail 15917 C57BL/6J ±  kb
transcript ENSMUST00000206092 Ensembl | MGI Sequence Detail 3358 Not Applicable  
polypeptide ENSMUSP00000146090 Ensembl | MGI Sequence Detail 359 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
References
more
  • Summaries
    All 43
    Gene Ontology 5
    Phenotypes 19
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory