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Tmed9 Gene Detail
Summary
  • Symbol
    Tmed9
  • Name
    transmembrane p24 trafficking protein 9
  • Synonyms
    2400003B06Rik, p24alpha2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914761
    NCBI Gene: 67511
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:55740948-55745510 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 30.06 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    52 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914761
protein coding gene Chr13:55721545-55745510 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020604
protein coding gene Chr13:55083372-55087900 (+)
A/J MGP_AJ_G0020558
protein coding gene Chr13:53047156-53051685 (+)
AKR/J MGP_AKRJ_G0020536
protein coding gene Chr13:54617964-54622492 (+)
BALB/cJ MGP_BALBcJ_G0020554
protein coding gene Chr13:53279580-53284109 (+)
C3H/HeJ MGP_C3HHeJ_G0020353
protein coding gene Chr13:54424738-54429267 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020988
protein coding gene Chr13:56745611-56750139 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018570
protein coding gene Chr13:50985206-50990112 (+)
CAST/EiJ MGP_CASTEiJ_G0019867
protein coding gene Chr13:54531579-54536126 (+)
CBA/J MGP_CBAJ_G0020313
protein coding gene Chr13:58926607-58931200 (+)
DBA/2J MGP_DBA2J_G0020436
protein coding gene Chr13:52598598-52603126 (+)
FVB/NJ MGP_FVBNJ_G0020415
protein coding gene Chr13:52069895-52074423 (+)
LP/J MGP_LPJ_G0020512
protein coding gene Chr13:55338210-55342764 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020444
protein coding gene Chr13:58386661-58391189 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021031
protein coding gene Chr13:54194148-54198676 (+)
PWK/PhJ MGP_PWKPhJ_G0019623
protein coding gene Chr13:52627817-52632167 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019450
protein coding gene Chr13:53114224-53118773 (+)
WSB/EiJ MGP_WSBEiJ_G0019929
protein coding gene Chr13:54553793-54558322 (+)



Homology
more
  • Human Ortholog
    TMED9, transmembrane p24 trafficking protein 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMED9, transmembrane p24 trafficking protein 9
  • Synonyms
    GMP25, HSGP25L2G, p24a2, p24alpha2, p25
  • Links
    NCBI Gene ID: 54732
    neXtProt AC: NX_Q9BVK6
    UniProt: Q9BVK6

  • Chr Location
    5q35.3; chr5:177592203-177597242 (+)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    17
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    13
  • Targeted
    2
  • Genomic Mutations
    2 involving Tmed9
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67511 NCBI Gene Model | MGI Sequence Detail 4563 C57BL/6J ±  kb
transcript NM_026211 RefSeq | MGI Sequence Detail 1463 C57BL/6  
polypeptide Q99KF1 UniProt | EBI | MGI Sequence Detail 235 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 135
    cDNA 134
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:221387 Liu L, et al., Pre-synaptic localization of the gamma-secretase-inhibiting protein p24alpha2 in the mammalian brain. J Neurochem. 2015 May;133(3):422-31

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory