About   Help   FAQ
Brd3 Gene Detail
Summary
  • Symbol
    Brd3
  • Name
    bromodomain containing 3
  • Synonyms
    2410084F24Rik, Fsrg2, ORFX, RINGL3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914632
    NCBI Gene: 67382
  • Alliance
    genome feature page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:27335588-27397669 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 19.38 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1848 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914632
 protein coding gene Chr2:27335588-27397674 (-)
129S1/SvImJ ENSMUSG00200052518
 protein coding gene Chr2:24295763-24357827 (-)
A/J ENSMUSG00195045781
 protein coding gene Chr2:24398133-24460235 (-)
AKR/J ENSMUSG00220052207
 protein coding gene Chr2:24515892-24577982 (-)
BALB/cJ ENSMUSG00180054286
 protein coding gene Chr2:24417127-24479224 (-)
C3H/HeJ ENSMUSG00175046274
 protein coding gene Chr2:24386468-24448561 (-)
C57BL/6NJ ENSMUSG00215046619
 protein coding gene Chr2:24445228-24507315 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023342
 protein coding gene Chr2:23303664-23362064 (-)
CAST/EiJ ENSTCUG00005051079
 protein coding gene Chr2:24132549-24195945 (-)
CBA/J ENSMUSG00210017656
 protein coding gene Chr2:24420105-24482199 (-)
DBA/2J ENSMUSG00185044815
 protein coding gene Chr2:24312170-24374256 (-)
FVB/NJ ENSMUSG00205047341
 protein coding gene Chr2:24163973-24226064 (-)
JF1/MsJ ENSUMUG00000053501
 protein coding gene Chr2:24218810-24282484 (-)
LP/J ENSMUSG00230040581
 protein coding gene Chr2:26231665-26293726 (-)
NOD/ShiLtJ ENSMUSG00190045667
 protein coding gene Chr2:24404808-24467088 (-)
NZO/HlLtJ ENSMUSG00225007952
 protein coding gene Chr2:33989134-34051215 (-)
PWK/PhJ ENSLUMG00010044966
 protein coding gene Chr2:24305961-24361233 (-)
SPRET/EiJ ENSMSPG00010041336
 protein coding gene Chr2:25031104-25095545 (-)
WSB/EiJ ENSIUOG00005050803
 protein coding gene Chr2:24269446-24331512 (-)



Homology
more
  • Human Ortholog
    BRD3, bromodomain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BRD3, bromodomain containing 3
  • Synonyms
    FSHRG2, ORFX, RING3L
  • Links
    NCBI Gene ID: 8019
    UniProt: Q15059

  • Chr Location
    9q34.2; chr9:134030305-134068555 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    44
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    696
  • Tissues
    68
  • cDNA Data
    192
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67382 NCBI Gene Model | MGI Sequence Detail 62082 C57BL/6J ±  kb
    transcript NM_023336 RefSeq | MGI Sequence Detail 5652 C57BL/6  
    polypeptide Q8K2F0 UniProt | EBI | MGI Sequence Detail 726 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 196
      cDNA 194
      Primer pair 2

      Microarray probesets 9
    Other
    Accession IDs
    less
    MGI:2139285
    References
    more
    • Summaries
      All 56
      Developmental Gene Expression 6
      Gene Ontology 7
      Phenotypes 15
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:380977 Wang N, et al., A non-canonical immunometabolic function of BRD3 during sepsis. Dev Cell. 2026 Feb 11;61(2):322-339.e6
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory