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Spmip10 Gene Detail
Summary
  • Symbol
    Spmip10
  • Name
    sperm microtubule inner protein 10
  • Synonyms
    1700065I17Rik, Tex43
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914593
    NCBI Gene: 67343
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:56721422-56727854 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 30.66 cM, cytoband D2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    31 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914593
 protein coding gene Chr18:56720690-56727855 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024443
 protein coding gene Chr18:55959002-55966330 (+)
A/J MGP_AJ_G0024409
 protein coding gene Chr18:53749617-53756036 (+)
AKR/J MGP_AKRJ_G0024379
 protein coding gene Chr18:55217578-55224259 (+)
BALB/cJ MGP_BALBcJ_G0024409
 protein coding gene Chr18:53931295-53938243 (+)
C3H/HeJ MGP_C3HHeJ_G0024176
 protein coding gene Chr18:55441216-55448532 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024855
 protein coding gene Chr18:57729180-57735596 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022287
 protein coding gene Chr18:53385256-53389978 (+)
CAST/EiJ MGP_CASTEiJ_G0023650
 protein coding gene Chr18:55461516-55469612 (+)
CBA/J MGP_CBAJ_G0024146
 protein coding gene Chr18:59534517-59540899 (+)
DBA/2J MGP_DBA2J_G0024276
 protein coding gene Chr18:53445493-53452257 (+)
FVB/NJ MGP_FVBNJ_G0024243
 protein coding gene Chr18:52834295-52841154 (+)
LP/J MGP_LPJ_G0024361
 protein coding gene Chr18:55922308-55930980 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024273
 protein coding gene Chr18:61215172-61221713 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024902
 protein coding gene Chr18:55337060-55345432 (+)
PWK/PhJ MGP_PWKPhJ_G0023394
 protein coding gene Chr18:53461030-53468155 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023200
 protein coding gene Chr18:55417822-55424107 (+)
WSB/EiJ MGP_WSBEiJ_G0023713
 protein coding gene Chr18:55259178-55265591 (+)



Homology
more
  • Human Ortholog
    SPMIP10, sperm microtubule inner protein 10
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPMIP10, sperm microtubule inner protein 10
  • Synonyms
    C5orf48, TEX43, Tseg7
  • Links
    NCBI Gene ID: 389320
    neXtProt AC: NX_Q6ZNM6
    UniProt: Q6ZNM6

  • Chr Location
    5q23.2; chr5:126631705-126636284 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit reduced sperm motility with normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032900 Ensembl Gene Model | MGI Sequence Detail 6433 C57BL/6J ±  kb
transcript ENSMUST00000035640 Ensembl | MGI Sequence Detail 565 Not Applicable  
polypeptide ENSMUSP00000038152 Ensembl | MGI Sequence Detail 141 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 4
References
more
  • Summaries
    All 25
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:338030 Zhou L, et al., Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility. Cell. 2023 Jun 22;186(13):2897-2910.e19
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory