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Lix1 Gene Detail
Summary
  • Symbol
    Lix1
  • Name
    limb and CNS expressed 1
  • Synonyms
    5730466L18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913893
    NCBI Gene: 66643
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:17622948-17679649 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 9.77 cM, cytoband A3.1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    229 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913893
 protein coding gene Chr17:17622934-17679649 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023181
 protein coding gene Chr17:15382171-15448124 (+)
A/J MGP_AJ_G0023146
 protein coding gene Chr17:15061124-15122167 (+)
AKR/J MGP_AKRJ_G0023116
 protein coding gene Chr17:15113149-15176451 (+)
BALB/cJ MGP_BALBcJ_G0023146
 protein coding gene Chr17:14991832-15052475 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0023589
 protein coding gene Chr17:16165360-16239631 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021102
 protein coding gene Chr17:12923120-12981121 (+)
CAST/EiJ MGP_CASTEiJ_G0022425
 protein coding gene Chr17:15137720-15201758 (+)
CBA/J MGP_CBAJ_G0022883
 protein coding gene Chr17:16715457-16782620 (+)
DBA/2J MGP_DBA2J_G0023016
 protein coding gene Chr17:14762438-14818918 (+)
FVB/NJ MGP_FVBNJ_G0022984
 protein coding gene Chr17:14590532-14654696 (+)
LP/J MGP_LPJ_G0023090
 protein coding gene Chr17:15370010-15431432 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023005
 protein coding gene Chr17:16247547-16310191 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023626
 protein coding gene Chr17:15298713-15362838 (+)
PWK/PhJ MGP_PWKPhJ_G0022174
 protein coding gene Chr17:14390880-14455320 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022002
 protein coding gene Chr17:14353745-14407961 (+)
WSB/EiJ MGP_WSBEiJ_G0022484
 protein coding gene Chr17:15575664-15639006 (+)



Homology
more
  • Human Ortholog
    LIX1, limb and CNS expressed 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LIX1, limb and CNS expressed 1
  • Synonyms
    C5orf11, Lft
  • Links
    NCBI Gene ID: 167410
    neXtProt AC: NX_Q8N485
    UniProt: Q8N485

  • Chr Location
    5q15; chr5:97091867-97142753 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
A gene trap allele that eliminates the full length transcript, but permits expression of a rodent-specific shorter transcript, results in mice with no overt mutant phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    963
  • Tissues
    234
  • cDNA Data
    12
  • Literature Summary
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66643 NCBI Gene Model | MGI Sequence Detail 56702 C57BL/6J ±  kb
transcript NM_025681 RefSeq | MGI Sequence Detail 3124 C57BL/6  
polypeptide Q6P566 UniProt | EBI | MGI Sequence Detail 282 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 12
    Primer pair 2
    Other 1

    Microarray probesets 5
References
more
  • Summaries
    All 38
    Developmental Gene Expression 12
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory