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Tm4sf20 Gene Detail
Summary
  • Symbol
    Tm4sf20
  • Name
    transmembrane 4 L six family member 20
  • Synonyms
    1810018L02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913511
    NCBI Gene: 66261
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:82734370-82746182 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 42.48 cM, cytoband C5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    174 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913511
protein coding gene Chr1:82734368-82746182 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016219
protein coding gene Chr1:83677746-83689557 (-)
A/J MGP_AJ_G0016202
protein coding gene Chr1:80709323-80721808 (-)
AKR/J MGP_AKRJ_G0016159
protein coding gene Chr1:82910570-82922422 (-)
BALB/cJ MGP_BALBcJ_G0016157
protein coding gene Chr1:80854118-80865931 (-)
C3H/HeJ MGP_C3HHeJ_G0015987
protein coding gene Chr1:83292849-83304661 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016610
protein coding gene Chr1:86904219-86916033 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014330
protein coding gene Chr1:75931671-75944350 (-)
CAST/EiJ MGP_CASTEiJ_G0015573
protein coding gene Chr1:82709529-82721330 (-)
CBA/J MGP_CBAJ_G0015961
protein coding gene Chr1:89696173-89708023 (-)
DBA/2J MGP_DBA2J_G0016062
protein coding gene Chr1:79999497-80011301 (-)
FVB/NJ MGP_FVBNJ_G0016065
protein coding gene Chr1:79093900-79105757 (-)
LP/J MGP_LPJ_G0016135
protein coding gene Chr1:84793865-84806283 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016085
protein coding gene Chr1:93087440-93099302 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016657
protein coding gene Chr1:83075332-83087133 (-)
PWK/PhJ MGP_PWKPhJ_G0015358
protein coding gene Chr1:79439882-79452586 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015136
protein coding gene Chr1:82271873-82283697 (-)
WSB/EiJ MGP_WSBEiJ_G0015633
protein coding gene Chr1:82875269-82887133 (-)



Homology
more
  • Human Ortholog
    TM4SF20, transmembrane 4 L six family member 20
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TM4SF20, transmembrane 4 L six family member 20
  • Synonyms
    PRO994, SLI5, TCCE518
  • Links
    NCBI Gene ID: 79853
    neXtProt AC: NX_Q53R12
    UniProt: Q53R12

  • Chr Location
    2q36.3; chr2:227362038-227381995 (-)  GRCh38

Human Diseases
more
  • Diseases
    1 with human TM4SF20 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000026149 Ensembl Gene Model | MGI Sequence Detail 11813 C57BL/6J ±  kb
    transcript ENSMUST00000027331 Ensembl | MGI Sequence Detail 1508 Not Applicable  
    polypeptide ENSMUSP00000027331 Ensembl | MGI Sequence Detail 226 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 24
      cDNA 23
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 5
      Gene Ontology 3
      Phenotypes 14
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/19/2024
    MGI 6.23
    The Jackson Laboratory