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Ube2d3 Gene Detail
Summary
  • Symbol
    Ube2d3
  • Name
    ubiquitin-conjugating enzyme E2D 3
  • Synonyms
    1100001F19Rik, 9430029A22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913355
    NCBI Gene: 66105
  • Alliance
    gene page
  • Transcription Start Sites
    19 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:135143993-135173975 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 62.56 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    160 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913355
 protein coding gene Chr3:135143910-135173975 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027907
 protein coding gene Chr3:138314714-138347558 (+)
A/J MGP_AJ_G0027865
 protein coding gene Chr3:133461955-133496823 (+)
AKR/J MGP_AKRJ_G0027830
 protein coding gene Chr3:136995898-137027249 (+)
BALB/cJ MGP_BALBcJ_G0027878
 protein coding gene Chr3:133318466-133348325 (+)
C3H/HeJ MGP_C3HHeJ_G0027607
 protein coding gene Chr3:137334389-137364669 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028321
 protein coding gene Chr3:143155831-143186544 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025659
 protein coding gene Chr3:128703030-128730917 (+)
CAST/EiJ MGP_CASTEiJ_G0027063
 protein coding gene Chr3:137068051-137101524 (+)
CBA/J MGP_CBAJ_G0027583
 protein coding gene Chr3:147995322-148028531 (+)
DBA/2J MGP_DBA2J_G0027723
 protein coding gene Chr3:132625917-132656875 (+)
FVB/NJ MGP_FVBNJ_G0027690
 protein coding gene Chr3:130115478-130145571 (+)
LP/J MGP_LPJ_G0027833
 protein coding gene Chr3:139755302-139788580 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027721
 protein coding gene Chr3:156116523-156148070 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028379
 protein coding gene Chr3:136535375-136566593 (+)
PWK/PhJ MGP_PWKPhJ_G0026787
 protein coding gene Chr3:132340226-132371427 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026613
 protein coding gene Chr3:134611007-134638238 (+)
WSB/EiJ MGP_WSBEiJ_G0027142
 protein coding gene Chr3:137321157-137352034 (+)



Homology
more
  • Human Ortholog
    UBE2D3, ubiquitin conjugating enzyme E2 D3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UBE2D3, ubiquitin conjugating enzyme E2 D3
  • Synonyms
    E2(17)KB3, UBC4/5, UBCH5C
  • Links
    NCBI Gene ID: 7323
    neXtProt AC: NX_P61077
    UniProt: P61077

  • Chr Location
    4q24; chr4:102794383-102868896 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    36
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    39
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66105 NCBI Gene Model | MGI Sequence Detail 29983 C57BL/6J ±  kb
    transcript NM_001356597 RefSeq | MGI Sequence Detail 4067 C57BL/6  
    polypeptide P61079 UniProt | EBI | MGI Sequence Detail 147 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 40
      cDNA 40

      Microarray probesets 12
    Other
    Accession IDs
    less
    MGI:1924549, MGI:2139576
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 10
      Phenotypes 14
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:305453 Roman-Trufero M, et al., Evolution of an Amniote-Specific Mechanism for Modulating Ubiquitin Signaling via Phosphoregulation of the E2 Enzyme UBE2D3. Mol Biol Evol. 2020 Jul 1;37(7):1986-2001
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory