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Sf3b6 Gene Detail
Summary
  • Symbol
    Sf3b6
  • Name
    splicing factor 3B, subunit 6
  • Synonyms
    0610009D07Rik, 6030419K15Rik, Sf3b14
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913305
    NCBI Gene: 66055
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:4867608-4877659 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 2.09 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    324 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913305
 protein coding gene Chr12:4867544-4877659 (+)
129S1/SvImJ ENSMUSG00200022321
 protein coding gene Chr12:1827535-1837652 (+)
A/J ENSMUSG00195014578
 protein coding gene Chr12:1855279-1865398 (+)
AKR/J ENSMUSG00220027356
 protein coding gene Chr12:1852812-1862933 (+)
BALB/cJ ENSMUSG00180014485
 protein coding gene Chr12:1851755-1861871 (+)
C3H/HeJ ENSMUSG00175009354
 protein coding gene Chr12:1830836-1840732 (+)
C57BL/6NJ ENSMUSG00215016754
 protein coding gene Chr12:1782362-1792482 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017590
 protein coding gene Chr12:1682124-1691578 (+)
CAST/EiJ ENSTCUG00005020744
 protein coding gene Chr12:1659744-1669985 (+)
CBA/J ENSMUSG00210013133
 protein coding gene Chr12:1850567-1860467 (+)
DBA/2J ENSMUSG00185020520
 protein coding gene Chr12:1834500-1844615 (+)
FVB/NJ ENSMUSG00205002690
 protein coding gene Chr12:1632202-1642319 (+)
JF1/MsJ ENSUMUG00000033395
 protein coding gene Chr12:1827274-1837480 (+)
LP/J ENSMUSG00230010338
 protein coding gene Chr12:3662565-3672680 (+)
NOD/ShiLtJ ENSMUSG00190007853
 protein coding gene Chr12:3074246-3084363 (+)
NZO/HlLtJ ENSMUSG00225017612
 protein coding gene Chr12:5722653-5732768 (+)
PWK/PhJ ENSLUMG00010016281
 protein coding gene Chr12:1653929-1664295 (+)
SPRET/EiJ ENSMSPG00010004762
 protein coding gene Chr12:2061845-2071754 (+)
WSB/EiJ ENSIUOG00005002058
 protein coding gene Chr12:1830879-1841060 (+)



Homology
more
  • Human Ortholog
    SF3B6, splicing factor 3b subunit 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SF3B6, splicing factor 3b subunit 6
  • Synonyms
    CGI-110, HSPC175, Ht006, P14, SAP14, SAP14a, SF3B14, SF3B14a
  • Links
    NCBI Gene ID: 51639
    UniProt: Q9Y3B4

  • Chr Location
    2p23.3; chr2:24067579-24076464 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    35
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    626
  • Tissues
    29
  • cDNA Data
    131
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66055 NCBI Gene Model | MGI Sequence Detail 10052 C57BL/6J ±  kb
transcript NM_025323 RefSeq | MGI Sequence Detail 1133 FVB/N  
polypeptide P59708 UniProt | EBI | MGI Sequence Detail 125 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 133
    cDNA 131
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:1924972, MGI:2142728
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:244597 Cui W, et al., Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. Sci Rep. 2016 Nov 21;6:37396
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory