About   Help   FAQ
Rbm8a Gene Detail
Summary
  • Symbol
    Rbm8a
  • Name
    RNA binding motif protein 8a
  • Synonyms
    2310057C03Rik, Rbm8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913129
    NCBI Gene: 60365
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:96537249-96541107 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 41.93 cM, cytoband H3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    161 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913129
 protein coding gene Chr3:96537244-96541107 (+)
129S1/SvImJ ENSMUSG00200040086
 protein coding gene Chr3:93165833-93169905 (+)
A/J ENSMUSG00195041421
 protein coding gene Chr3:93569322-93573389 (+)
AKR/J ENSMUSG00220039374
 protein coding gene Chr3:91915057-91918915 (+)
BALB/cJ ENSMUSG00180040656
 protein coding gene Chr3:93511275-93515333 (+)
C3H/HeJ ENSMUSG00175027866
 protein coding gene Chr3:93127742-93131807 (+)
C57BL/6NJ ENSMUSG00215015749
 protein coding gene Chr3:93892452-93896310 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025383
 protein coding gene Chr3:90673294-90677117 (+)
CAST/EiJ ENSTCUG00005018846
 protein coding gene Chr3:93711985-93716054 (+)
CBA/J ENSMUSG00210050828
 protein coding gene Chr3:93680767-93684833 (+)
DBA/2J ENSMUSG00185040579
 protein coding gene Chr3:94133481-94137339 (+)
FVB/NJ ENSMUSG00205013519
 protein coding gene Chr3:92789164-92793231 (+)
JF1/MsJ ENSUMUG00000023150
 protein coding gene Chr3:92977018-92980883 (+)
LP/J ENSMUSG00230038994
 protein coding gene Chr3:96097673-96101744 (+)
NOD/ShiLtJ ENSMUSG00190037619
 protein coding gene Chr3:94226402-94230473 (+)
NZO/HlLtJ ENSMUSG00225008802
 protein coding gene Chr3:98476511-98480568 (+)
PWK/PhJ ENSLUMG00010025685
 protein coding gene Chr3:92969826-92973695 (+)
SPRET/EiJ ENSMSPG00010036950
 protein coding gene Chr3:93268238-93272655 (+)
WSB/EiJ ENSIUOG00005029923
 protein coding gene Chr3:93627749-93631816 (+)



Homology
more
  • Human Ortholog
    RBM8A, RNA binding motif protein 8A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RBM8A, RNA binding motif protein 8A
  • Synonyms
    BOV-1A, BOV-1B, BOV-1C, C1DELq21.1, DEL1q21.1, MDS014, RBM8, TAR, Y14, ZNRP, ZRNP1
  • Links
    NCBI Gene ID: 9939
    UniProt: Q9Y5S9

  • Chr Location
    1q21.1; chr1:145921065-145928067 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human RBM8A associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotypes from 1 allele in 2 genetic backgrounds
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    49
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    639
  • Tissues
    38
  • cDNA Data
    80
  • Literature Summary
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038374 Ensembl Gene Model | MGI Sequence Detail 3859 C57BL/6J ±  kb
    transcript ENSMUST00000196456 Ensembl | MGI Sequence Detail 2604 Not Applicable  
    polypeptide ENSMUSP00000143190 Ensembl | MGI Sequence Detail 174 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 83
      Genomic 1
      cDNA 80
      Primer pair 2
      Antibodies 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1914219, MGI:2138122
    References
    more
    • Summaries
      All 61
      Developmental Gene Expression 9
      Diseases 1
      Gene Ontology 11
      Phenotypes 18
    • Earliest
      J:60627 Zhao XF, et al., MAGOH interacts with a novel RNA-binding protein. Genomics. 2000 Jan 1;63(1):145-8
    • Latest
      J:366718 Alsina FC, et al., The RNA-binding protein EIF4A3 promotes axon development by direct control of the cytoskeleton. Cell Rep. 2024 Sep 24;43(9):114666
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory