About   Help   FAQ
Rnf25 Gene Detail
Summary
  • Symbol
    Rnf25
  • Name
    ring finger protein 25
  • Synonyms
    0610009H16Rik, AO7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890215
    NCBI Gene: 57751
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:74632907-74640556 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 38.54 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    217 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890215
 protein coding gene Chr1:74632907-74640556 (-)
129S1/SvImJ ENSMUSG00200032777
 protein coding gene Chr1:72295990-72303636 (-)
A/J ENSMUSG00195008432
 protein coding gene Chr1:71720794-71728446 (-)
AKR/J ENSMUSG00220010347
 protein coding gene Chr1:71866634-71874284 (-)
BALB/cJ ENSMUSG00180017120
 protein coding gene Chr1:71979621-71987272 (-)
C3H/HeJ ENSMUSG00175015412
 protein coding gene Chr1:72121165-72128816 (-)
C57BL/6NJ ENSMUSG00215011727
 protein coding gene Chr1:72024948-72032597 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014269
 protein coding gene Chr1:68151834-68159455 (-)
CAST/EiJ ENSTCUG00005028125
 protein coding gene Chr1:71749653-71757283 (-)
CBA/J ENSMUSG00210035335
 protein coding gene Chr1:71805411-71813057 (-)
DBA/2J ENSMUSG00185029941
 protein coding gene Chr1:72899360-72907007 (-)
FVB/NJ ENSMUSG00205018911
 protein coding gene Chr1:71474555-71482205 (-)
JF1/MsJ ENSUMUG00000004931
 protein coding gene Chr1:71799510-71806951 (-)
LP/J ENSMUSG00230011076
 protein coding gene Chr1:72889157-72896803 (-)
NOD/ShiLtJ ENSMUSG00190034182
 protein coding gene Chr1:72031172-72038820 (-)
NZO/HlLtJ ENSMUSG00225039938
 protein coding gene Chr1:76104270-76111916 (-)
PWK/PhJ ENSLUMG00010013144
 protein coding gene Chr1:71383112-71390555 (-)
SPRET/EiJ ENSMSPG00010017993
 protein coding gene Chr1:73474673-73482117 (-)
WSB/EiJ ENSIUOG00005012320
 protein coding gene Chr1:71652968-71660622 (-)



Homology
more
  • Human Ortholog
    RNF25, ring finger protein 25
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNF25, ring finger protein 25
  • Synonyms
    AO7
  • Links
    NCBI Gene ID: 64320
    UniProt: Q96BH1

  • Chr Location
    2q35; chr2:218663866-218672006 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    698
  • Tissues
    94
  • cDNA Data
    14
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 57751 NCBI Gene Model | MGI Sequence Detail 7650 C57BL/6J ±  kb
    transcript NM_021313 RefSeq | MGI Sequence Detail 1498 C57BL/6  
    polypeptide Q9QZR0 UniProt | EBI | MGI Sequence Detail 456 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 14

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1913312
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 5
      Gene Ontology 9
      Phenotypes 20
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory