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Erbin Gene Detail
Summary
  • Symbol
    Erbin
  • Name
    Erbb2 interacting protein
  • Synonyms
    1700028E05Rik, Erbb2ip, Erbin, mKIAA1225
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890169
    NCBI Gene: 59079
  • Alliance
    genome feature page
  • Transcription Start Sites
    23 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:103955295-104057022 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 56.16 cM, cytoband D1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2210 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890169
 protein coding gene Chr13:103955294-104057094 (-)
129S1/SvImJ ENSMUSG00200007445
 protein coding gene Chr13:98369199-98470917 (-)
A/J ENSMUSG00195027395
 protein coding gene Chr13:98969864-99074507 (-)
AKR/J ENSMUSG00220026435
 protein coding gene Chr13:97398667-97503316 (-)
BALB/cJ ENSMUSG00180033543
 protein coding gene Chr13:99516625-99618370 (-)
C3H/HeJ ENSMUSG00175016467
 protein coding gene Chr13:99615432-99717159 (-)
C57BL/6NJ ENSMUSG00215028196
 protein coding gene Chr13:99602258-99703993 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018856
 protein coding gene Chr13:97402441-97504737 (-)
CAST/EiJ ENSTCUG00005011031
 protein coding gene Chr13:98731358-98834294 (-)
CBA/J ENSMUSG00210011362
 protein coding gene Chr13:98936439-99038166 (-)
DBA/2J ENSMUSG00185026247
 protein coding gene Chr13:102689897-102791350 (-)
FVB/NJ ENSMUSG00205023803
 protein coding gene Chr13:98373949-98475682 (-)
JF1/MsJ ENSUMUG00000006246
 protein coding gene Chr13:102283096-102385023 (-)
LP/J ENSMUSG00230006011
 protein coding gene Chr13:112838920-112940648 (-)
NOD/ShiLtJ ENSMUSG00190030842
 protein coding gene Chr13:99273251-99377888 (-)
NZO/HlLtJ ENSMUSG00225036899
 protein coding gene Chr13:105187479-105289342 (-)
PWK/PhJ ENSLUMG00010024233
 protein coding gene Chr13:98339626-98441515 (-)
SPRET/EiJ ENSMSPG00010008906
 protein coding gene Chr13:99732134-99849019 (-)
WSB/EiJ ENSIUOG00005034245
 protein coding gene Chr13:98373670-98475532 (-)



Homology
more
  • Human Ortholog
    ERBIN, erbb2 interacting protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ERBIN, erbb2 interacting protein
  • Synonyms
    ERBB2IP, HEL-S-78, LAP2
  • Links
    NCBI Gene ID: 55914
    UniProt: Q96RT1

  • Chr Location
    5q12.3; chr5:65883128-66082546 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 1 genetic background
    4 images
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null or gene trapped allele exhibit impaired myelination, reduced nerve conduction, and hyporesponsiveness to tactile stimuli.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    609
  • Tissues
    8
  • cDNA Data
    16
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021709 Ensembl Gene Model | MGI Sequence Detail 101728 C57BL/6J ±  kb
transcript ENSMUST00000191275 Ensembl | MGI Sequence Detail 5552 Not Applicable  
polypeptide ENSMUSP00000140536 Ensembl | MGI Sequence Detail 1450 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 19

    Microarray probesets 7
Other
Accession IDs
less
MGI:1919511
References
more
  • Summaries
    All 63
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 15
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:389864 Murata K, et al., A novel miniTurbo knock-in mouse reveals a protein interaction network of USP46 in the brain. Exp Anim. 2026 Jan 1;75(1):63-72
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory