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Pidd1 Gene Detail
Summary
  • Symbol
    Pidd1
  • Name
    p53 induced death domain protein 1
  • Synonyms
    1200011D09Rik, Lrdd, Pidd
  • Feature Type
    protein coding gene
  • IDs
    MGI:1889507
    NCBI Gene: 57913
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:141018026-141023938 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 86.79 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    176 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1889507
 protein coding gene Chr7:141018026-141027477 (-)
129S1/SvImJ ENSMUSG00200041706
 protein coding gene Chr7:127583610-127589522 (-)
A/J ENSMUSG00195034425
 protein coding gene Chr7:132066097-132072009 (-)
AKR/J ENSMUSG00220031302
 protein coding gene Chr7:125547770-125553682 (-)
BALB/cJ ENSMUSG00180030935
 protein coding gene Chr7:128758253-128764165 (-)
C3H/HeJ ENSMUSG00175039390
 protein coding gene Chr7:129486514-129492426 (-)
C57BL/6NJ ENSMUSG00215044315
 protein coding gene Chr7:128753096-128759008 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030697
 protein coding gene Chr7:143644132-143650001 (-)
CAST/EiJ ENSTCUG00005049167
 protein coding gene Chr7:132058301-132064202 (-)
CBA/J ENSMUSG00210028058
 protein coding gene Chr7:129244514-129250426 (-)
DBA/2J ENSMUSG00185016428
 protein coding gene Chr7:133523059-133528971 (-)
FVB/NJ ENSMUSG00205026133
 protein coding gene Chr7:129165335-129171247 (-)
JF1/MsJ ENSUMUG00000024564
 protein coding gene Chr7:138600887-138606797 (-)
LP/J ENSMUSG00230038381
 protein coding gene Chr7:139686521-139692433 (-)
NOD/ShiLtJ ENSMUSG00190018037
 protein coding gene Chr7:129351964-129357876 (-)
NZO/HlLtJ ENSMUSG00225051780
 protein coding gene Chr7:137895706-137901618 (-)
PWK/PhJ ENSLUMG00010038066
 protein coding gene Chr7:127731760-127737669 (-)
SPRET/EiJ ENSMSPG00010039763
 protein coding gene Chr7:129176738-129182634 (-)
WSB/EiJ ENSIUOG00005032595
 protein coding gene Chr7:130085511-130091423 (-)



Homology
more
  • Human Ortholog
    PIDD1, p53-induced death domain protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PIDD1, p53-induced death domain protein 1
  • Synonyms
    altPIDD1, LRDD, MRT75, PIDD
  • Links
    NCBI Gene ID: 55367
    UniProt: C0HMD6, Q9HB75

  • Chr Location
    11p15.5; chr11:799179-809753 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human PIDD1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    18 phenotype references
Mice homozygous for a null allele were viable and did not show fertility problems, sex bias, other overt phenotype, or any gross abnormalities in histological assessment.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    55
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    667
  • Tissues
    11
  • cDNA Data
    38
  • Literature Summary
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025507 Ensembl Gene Model | MGI Sequence Detail 5913 C57BL/6J ±  kb
transcript ENSMUST00000106005 Ensembl | MGI Sequence Detail 2900 Not Applicable  
polypeptide ENSMUSP00000101627 Ensembl | MGI Sequence Detail 915 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    Genomic 1
    cDNA 39

    Microarray probesets 4
Other
Accession IDs
less
MGI:1918981, MGI:2142154
References
more
  • Summaries
    All 61
    Developmental Gene Expression 6
    Gene Ontology 10
    Phenotypes 18
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:387190 Fang Y, et al., TUT1-catalyzed U6 snRNA 3'-end maturation is essential for RNA splicing and stem cell survival. EMBO Rep. 2026 May;27(10):2703-2730
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory