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Rbm38 Gene Detail
Summary
  • Symbol
    Rbm38
  • Name
    RNA binding motif protein 38
  • Synonyms
    Rnpc1, Seb4l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1889294
    NCBI Gene: 56190
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:172863722-172876527 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 95.67 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    316 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1889294
 protein coding gene Chr2:172862291-172876527 (+)
129S1/SvImJ ENSMUSG00200039163
 protein coding gene Chr2:169794426-169808658 (+)
A/J ENSMUSG00195023998
 protein coding gene Chr2:170122846-170137078 (+)
AKR/J ENSMUSG00220032228
 protein coding gene Chr2:169418526-169432758 (+)
BALB/cJ ENSMUSG00180035774
 protein coding gene Chr2:169559510-169573732 (+)
C3H/HeJ ENSMUSG00175039415
 protein coding gene Chr2:170329199-170343421 (+)
C57BL/6NJ ENSMUSG00215015781
 protein coding gene Chr2:169758094-169772330 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024745
 protein coding gene Chr2:164972043-164984986 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210035917
 protein coding gene Chr2:170239459-170253681 (+)
DBA/2J ENSMUSG00185024813
 protein coding gene Chr2:169953035-169967257 (+)
FVB/NJ ENSMUSG00205015147
 protein coding gene Chr2:169009600-169023832 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230011062
 protein coding gene Chr2:171530813-171545045 (+)
NOD/ShiLtJ ENSMUSG00190035026
 protein coding gene Chr2:169639722-169653944 (+)
NZO/HlLtJ ENSMUSG00225002425
 protein coding gene Chr2:179515775-179529992 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    RBM38, RNA binding motif protein 38
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RBM38, RNA binding motif protein 38
  • Synonyms
    dJ800J21.2, HSRNASEB, RNPC1, SEB4B, SEB4D
  • Links
    NCBI Gene ID: 55544
    UniProt: Q9H0Z9

  • Chr Location
    20q13.31; chr20:57391396-57409333 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 1 allele in 1 genetic background
    9 phenotypes from multigenic genotypes
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display premature aging and death with increased tumor incidence and hematopoietic defects including extramedullary hematopoiesis and anemia.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    21
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    662
  • Tissues
    58
  • cDNA Data
    72
  • Literature Summary
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56190 NCBI Gene Model | MGI Sequence Detail 12806 C57BL/6J ±  kb
    transcript NM_019547 RefSeq | MGI Sequence Detail 1750 C57BL/6  
    polypeptide Q62176 UniProt | EBI | MGI Sequence Detail 237 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 79
      Genomic 1
      cDNA 73
      Primer pair 5

      Microarray probesets 3
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 9
      Gene Ontology 6
      Phenotypes 11
    • Earliest
      J:63186 Fetka I, et al., Expression of the RNA recognition motif-containing protein SEB-4 during xenopus embryonic development. Mech Dev. 2000 Jun;94(1-2):283-6
    • Latest
      J:384798 Rayee D, et al., RNA-binding proteins in the mouse lens: Functional classifications, expression profiling, and interaction studies of Carhsp1 with crystallin mRNAs. Dev Biol. 2026 Apr 28;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory