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Nom1 Gene Detail
Summary
  • Symbol
    Nom1
  • Name
    nucleolar protein with MIF4G domain 1
  • Synonyms
    D5Kng1, Gm1040, LOC381627
  • Feature Type
    protein coding gene
  • IDs
    MGI:1861749
    NCBI Gene: 433864
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:29637338-29658504 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 15.00 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    136 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1861749
 protein coding gene Chr5:29637338-29662841 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029375
 protein coding gene Chr5:27356689-27386403 (+)
A/J MGP_AJ_G0029341
 protein coding gene Chr5:26444825-26470181 (+)
AKR/J MGP_AKRJ_G0029292
 protein coding gene Chr5:27520713-27543394 (+)
BALB/cJ MGP_BALBcJ_G0029352
 protein coding gene Chr5:26986673-27009525 (+)
C3H/HeJ MGP_C3HHeJ_G0029073
 protein coding gene Chr5:27538327-27561843 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029805
 protein coding gene Chr5:29020350-29048685 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027043
 protein coding gene Chr5:24001270-24025439 (+)
CAST/EiJ MGP_CASTEiJ_G0028484
 protein coding gene Chr5:26643783-26669108 (+)
CBA/J MGP_CBAJ_G0029041
 protein coding gene Chr5:29547589-29577407 (+)
DBA/2J MGP_DBA2J_G0029190
 protein coding gene Chr5:26652694-26675830 (+)
FVB/NJ MGP_FVBNJ_G0029148
 protein coding gene Chr5:26060941-26084990 (+)
LP/J MGP_LPJ_G0029275
 protein coding gene Chr5:27805082-27829814 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029177
 protein coding gene Chr5:30545240-30569465 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029839
 protein coding gene Chr5:27106656-27132010 (+)
PWK/PhJ MGP_PWKPhJ_G0028208
 protein coding gene Chr5:25758998-25782593 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028039
 protein coding gene Chr5:26396675-26421461 (+)
WSB/EiJ MGP_WSBEiJ_G0028564
 protein coding gene Chr5:27134996-27161948 (+)



Homology
more
  • Human Ortholog
    NOM1, nucleolar protein with MIF4G domain 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NOM1, nucleolar protein with MIF4G domain 1
  • Synonyms
    C7orf3, PPP1R113, SGD1
  • Links
    NCBI Gene ID: 64434
    neXtProt AC: NX_Q5C9Z4
    UniProt: Q5C9Z4

  • Chr Location
    7q36.3; chr7:156949712-156973176 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    26 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Radiation induced
    3
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    6 involving Nom1
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    33 strains or lines available
Female mice heterozygous for a knock-out allele show anomalies in the growth phase of the hair cycle (anagen).
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    766
  • Tissues
    13
  • cDNA Data
    43
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 433864 NCBI Gene Model | MGI Sequence Detail 21167 C57BL/6J ±  kb
transcript NR_153385 RefSeq | MGI Sequence Detail 3583 ZRU/MplStud  
polypeptide Q3UFM5 UniProt | EBI | MGI Sequence Detail 854 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 44
    cDNA 43
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:2685886
References
more
  • Summaries
    All 50
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 4
    Phenotypes 26
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory