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Gnasas1 Gene Detail
Summary
  • Symbol
    Gnasas1
  • Name
    GNAS antisense RNA 1
  • Synonyms
    Gnas-as, Nespas
Location &
Maps
more
  • Sequence Map
    Chr2:174123030-174137229 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 97.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    282 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1861674
 antisense lncRNA gene Chr2:174108218-174137279 (-)
129S1/SvImJ ENSMUSG00200040503
 lncRNA gene Chr2:171060077-171074259 (-)
A/J ENSMUSG00195025164
 lncRNA gene Chr2:171388651-171402833 (-)
AKR/J ENSMUSG00220038198
 lncRNA gene Chr2:170683155-170697274 (-)
BALB/cJ ENSMUSG00180039714
 lncRNA gene Chr2:170821776-170835896 (-)
C3H/HeJ ENSMUSG00175042502
 lncRNA gene Chr2:171593660-171607869 (-)
C57BL/6NJ ENSMUSG00215033230
 lncRNA gene Chr2:171020909-171035122 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0003328
 antisense lncRNA gene Chr2:166257775-166272225 (-)
CAST/EiJ ENSTCUG00005009116
 lncRNA gene Chr2:169924379-169938515 (-)
CBA/J ENSMUSG00210043247
 lncRNA gene Chr2:171503845-171517940 (-)
DBA/2J ENSMUSG00185027077
 lncRNA gene Chr2:171217484-171231697 (-)
FVB/NJ ENSMUSG00205025721
 lncRNA gene Chr2:170274192-170288311 (-)
JF1/MsJ ENSUMUG00000048603
 lncRNA gene Chr2:170904576-170918649 (-)
LP/J ENSMUSG00230014143
 lncRNA gene Chr2:172796362-172810544 (-)
NOD/ShiLtJ ENSMUSG00190045942
 lncRNA gene Chr2:170900978-170915094 (-)
NZO/HlLtJ ENSMUSG00225004122
 lncRNA gene Chr2:180788626-180802748 (-)
PWK/PhJ ENSLUMG00010038771
 lncRNA gene Chr2:170800260-170814333 (-)
SPRET/EiJ ENSMSPG00010028591
 lncRNA gene Chr2:173588595-173602751 (-)
WSB/EiJ ENSIUOG00005027215
 lncRNA gene Chr2:170646892-170661075 (-)



Homology
more
  • Human Ortholog
    GNAS-AS1, GNAS antisense RNA 1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GNAS-AS1, GNAS antisense RNA 1
  • Synonyms
    GNAS1AS, GNAS-AS, GNASAS, NCRNA00075, NESP-AS, NESPAS, SANG
  • Links
    NCBI Gene ID: 149775

  • Chr Location
    20q13.32; chr20:58818893-58855296 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Gnasas1 mouse models; 1 with human GNAS-AS1 associations

Human Disease Mouse Models
      
IDs
 View 2 models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 4 alleles in 4 genetic backgrounds
    1 phenotype from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice heterozygous for a knock-out allele exhibit postnatal lethality, abnormal suckling, lethargy, decreased body size, and altered maternal imprinting.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    621
  • Tissues
    13
  • cDNA Data
    2
  • Literature Summary
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      47
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56802 NCBI Gene Model | MGI Sequence Detail 14200 C57BL/6J ±  kb
    transcript NR_002846 RefSeq | MGI Sequence Detail 2248 ZRU/MplStud  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 3
      Primer pair 3
      Other 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:6305888
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 9
      Diseases 1
      Phenotypes 10
    • Earliest
      J:61327 Wroe SF, et al., An imprinted transcript, antisense to Nesp, adds complexity to the cluster of imprinted genes at the mouse Gnas locus. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3342-6
    • Latest
      J:381083 Hanin G, et al., ZFP57 is a regulator of postnatal growth and life-long health. Nat Commun. 2026 Jan 27;17(1)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory