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Eif3i Gene Detail
Summary
  • Symbol
    Eif3i
  • Name
    eukaryotic translation initiation factor 3, subunit I
  • Synonyms
    36kDa, D4Ertd632e, Eif3s2, TRIP-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1860763
    NCBI Gene: 54709
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:129485767-129494441 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 63.26 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    82 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1860763
 protein coding gene Chr4:129485753-129494441 (-)
129S1/SvImJ ENSMUSG00200020052
 protein coding gene Chr4:122924621-122933303 (-)
A/J ENSMUSG00195036738
 protein coding gene Chr4:124260437-124269108 (-)
AKR/J ENSMUSG00220045954
 protein coding gene Chr4:123251953-123260641 (-)
BALB/cJ ENSMUSG00180047885
 protein coding gene Chr4:121894113-121902802 (-)
C3H/HeJ ENSMUSG00175044202
 protein coding gene Chr4:122906724-122915412 (-)
C57BL/6NJ ENSMUSG00215051351
 protein coding gene Chr4:124410000-124418688 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026526
 protein coding gene Chr4:119398926-119407596 (-)
CAST/EiJ ENSTCUG00005043193
 protein coding gene Chr4:123790475-123799071 (-)
CBA/J ENSMUSG00210053586
 protein coding gene Chr4:122535738-122544427 (-)
DBA/2J ENSMUSG00185051753
 protein coding gene Chr4:124068087-124076775 (-)
FVB/NJ ENSMUSG00205038800
 protein coding gene Chr4:122294662-122303363 (-)
JF1/MsJ ENSUMUG00000028747
 protein coding gene Chr4:124713012-124721700 (-)
LP/J ENSMUSG00230032980
 protein coding gene Chr4:127861912-127870967 (-)
NOD/ShiLtJ ENSMUSG00190043293
 protein coding gene Chr4:122299560-122308242 (-)
NZO/HlLtJ ENSMUSG00225024565
 protein coding gene Chr4:133778825-133787913 (-)
PWK/PhJ ENSLUMG00010045401
 protein coding gene Chr4:121753136-121761833 (-)
SPRET/EiJ ENSMSPG00010043699
 protein coding gene Chr4:123820506-123829001 (-)
WSB/EiJ ENSIUOG00005041386
 protein coding gene Chr4:122160538-122169220 (-)



Homology
more
  • Human Ortholog
    EIF3I, eukaryotic translation initiation factor 3 subunit I
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EIF3I, eukaryotic translation initiation factor 3 subunit I
  • Synonyms
    eIF3-beta, eIF3-p36, EIF3S2, PRO2242, TRIP-1, TRIP1
  • Links
    NCBI Gene ID: 8668
    UniProt: Q13347

  • Chr Location
    1p35.2; chr1:32221077-32245397 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    661
  • Tissues
    35
  • cDNA Data
    293
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 54709 NCBI Gene Model | MGI Sequence Detail 8675 C57BL/6J ±  kb
transcript NM_018799 RefSeq | MGI Sequence Detail 1127 ZRU/MplStud  
polypeptide Q9QZD9 UniProt | EBI | MGI Sequence Detail 325 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000006981 eukaryotic translation initiation factor 3 subunit I
    (term hierarchy)
  • InterPro Domains
    IPR024977 Anaphase-promoting complex subunit 4-like, WD40 domain
    IPR027525 Eukaryotic translation initiation factor 3 subunit I
    IPR001680 WD40 repeat
    IPR019775 WD40 repeat, conserved site
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
  • GlyGen
    Q9QZD9 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 294
    cDNA 293
    Primer pair 1
    Antibodies 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:1277123
References
more
  • Summaries
    All 50
    Developmental Gene Expression 2
    Gene Ontology 11
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:274162 Nyp MF, et al., Lung epithelial-specific TRIP-1 overexpression maintains epithelial integrity during hyperoxia exposure. Physiol Rep. 2018 Mar;6(5)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory