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Atp8b2 Gene Detail
Summary
  • Symbol
    Atp8b2
  • Name
    ATPase, class I, type 8B, member 2
  • Synonyms
    Id
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859660
    NCBI Gene: 54667
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:89846795-89870645 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 39.19 cM, cytoband F2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    635 from dbSNP Build 142
  • Strain Annotations
    27
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859660
 protein coding gene Chr3:89846788-89870815 (-)
129S1/SvImJ ENSMUSGG00200054449
 protein coding gene Chr3:86716902-86720513 (-)
129S1/SvImJ ENSMUSG00200035774
 protein coding gene Chr3:86720639-86723773 (-)
A/J ENSMUSG00195052674
 protein coding gene Chr3:86735794-86738928 (-)
A/J ENSMUSGG00195054962
 protein coding gene Chr3:86732059-86735668 (-)
AKR/J ENSMUSG00220050681
 protein coding gene Chr3:86690298-86693432 (-)
AKR/J ENSMUSGG00220054339
 protein coding gene Chr3:86686561-86690172 (-)
BALB/cJ ENSMUSG00180048342
 protein coding gene Chr3:86827571-86830704 (-)
BALB/cJ ENSMUSGG00180055488
 protein coding gene Chr3:86823786-86827444 (-)
C3H/HeJ ENSMUSG00175046678
 protein coding gene Chr3:86668351-86671485 (-)
C3H/HeJ ENSMUSGG00175055082
 protein coding gene Chr3:86664614-86668225 (-)
C57BL/6NJ ENSMUSG00215046389
 protein coding gene Chr3:87108405-87111539 (-)
C57BL/6NJ ENSMUSGG00215055274
 protein coding gene Chr3:87104668-87108279 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025220
 protein coding gene Chr3:82685530-82709661 (-)
CAST/EiJ no annotation
CBA/J ENSMUSGG00210054548
 protein coding gene Chr3:86802267-86805878 (-)
CBA/J ENSMUSG00210041032
 protein coding gene Chr3:86806004-86809138 (-)
DBA/2J ENSMUSGG00185057452
 protein coding gene Chr3:86912193-86915851 (-)
DBA/2J ENSMUSG00185050767
 protein coding gene Chr3:86915978-86919111 (-)
FVB/NJ ENSMUSG00205045357
 protein coding gene Chr3:85729993-85733127 (-)
FVB/NJ ENSMUSGG00205054629
 protein coding gene Chr3:85726256-85729867 (-)
JF1/MsJ no annotation
LP/J ENSMUSGG00230055316
 protein coding gene Chr3:88938153-88941764 (-)
LP/J ENSMUSG00230031222
 protein coding gene Chr3:88941890-88945024 (-)
NOD/ShiLtJ ENSMUSG00190031090
 protein coding gene Chr3:87194579-87197712 (-)
NOD/ShiLtJ ENSMUSGG00190054602
 protein coding gene Chr3:87190801-87194452 (-)
NZO/HlLtJ ENSMUSGG00225055156
 protein coding gene Chr3:91696304-91699962 (-)
NZO/HlLtJ ENSMUSG00225011867
 protein coding gene Chr3:91700089-91703222 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010049556
 protein coding gene Chr3:87416179-87440111 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ATP8B2, ATPase phospholipid transporting 8B2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP8B2, ATPase phospholipid transporting 8B2
  • Synonyms
    ATPID
  • Links
    NCBI Gene ID: 57198
    UniProt: P98198

  • Chr Location
    1q21.3; chr1:154325520-154351307 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    834
  • Tissues
    30
  • cDNA Data
    89
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 54667 NCBI Gene Model | MGI Sequence Detail 23851 C57BL/6J ±  kb
    transcript NM_001368650 RefSeq | MGI Sequence Detail 5520 C57BL/6  
    polypeptide P98199 UniProt | EBI | MGI Sequence Detail 1209 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 89
      cDNA 89

      Microarray probesets 4
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 9
      Phenotypes 14
    • Earliest
      J:29458 Shoji W, et al., MIDA1, a protein associated with Id, regulates cell growth. J Biol Chem. 1995 Oct 20;270(42):24818-25
    • Latest
      J:363294 Wang S, et al., SOX4 facilitates brown fat development and maintenance through EBF2-mediated thermogenic gene program in mice. Cell Death Differ. 2025 Mar;32(3):447-465
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory