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Praf2 Gene Detail
Summary
  • Symbol
    Praf2
  • Name
    PRA1 domain family 2
  • Synonyms
    DXImx39e, JM4, Sfc20
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859607
    NCBI Gene: 54637
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:7594810-7597302 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 3.48 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    16 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859607
 protein coding gene ChrX:7594678-7597303 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035521
 protein coding gene ChrX:2343272-2345897 (+)
A/J MGP_AJ_G0035499
 protein coding gene ChrX:2305679-2308272 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0035495
 protein coding gene ChrX:2327280-2329905 (+)
C3H/HeJ MGP_C3HHeJ_G0035203
 protein coding gene ChrX:2389524-2392897 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036019
 protein coding gene ChrX:2424723-2430514 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032895
 protein coding gene ChrX:1872047-1874665 (+)
CAST/EiJ MGP_CASTEiJ_G0034504
 protein coding gene ChrX:2281021-2283388 (+)
CBA/J MGP_CBAJ_G0035173
 protein coding gene ChrX:2550252-2553365 (+)
DBA/2J MGP_DBA2J_G0035330
 protein coding gene ChrX:2331477-2334102 (+)
FVB/NJ MGP_FVBNJ_G0035277
 protein coding gene ChrX:2288180-2291265 (+)
LP/J MGP_LPJ_G0035408
 protein coding gene ChrX:2365689-2369130 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035317
 protein coding gene ChrX:2503380-2520367 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036037
 protein coding gene ChrX:2330047-2333557 (+)
PWK/PhJ MGP_PWKPhJ_G0034205
 protein coding gene ChrX:2263924-2266548 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034043
 protein coding gene ChrX:2296143-2298773 (+)
WSB/EiJ MGP_WSBEiJ_G0034627
 protein coding gene ChrX:2336999-2340689 (+)



Homology
more
  • Human Ortholog
    PRAF2, PRA1 domain family member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRAF2, PRA1 domain family member 2
  • Synonyms
    JM4, Yip6a
  • Links
    NCBI Gene ID: 11230
    neXtProt AC: NX_O60831
    UniProt: O60831

  • Chr Location
    Xp11.23; chrX:49071161-49074002 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    725
  • Tissues
    3
  • cDNA Data
    45
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 54637 NCBI Gene Model | MGI Sequence Detail 2493 C57BL/6J ±  kb
transcript NM_138602 RefSeq | MGI Sequence Detail 1206 ZRU/MplStud  
polypeptide Q9JIG8 UniProt | EBI | MGI Sequence Detail 178 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 50
    Genomic 5
    cDNA 45

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140183, MGI:2148054
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory