About   Help   FAQ
Syt11 Gene Detail
Summary
  • Symbol
    Syt11
  • Name
    synaptotagmin XI
  • Synonyms
    6530420C11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859547
    NCBI Gene: 229521
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:88652006-88682466 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 38.96 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    651 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859547
 protein coding gene Chr3:88652006-88682471 (-)
129S1/SvImJ ENSMUSG00200037098
 protein coding gene Chr3:85506913-85537380 (-)
A/J ENSMUSG00195051877
 protein coding gene Chr3:85521951-85552077 (-)
AKR/J ENSMUSG00220050091
 protein coding gene Chr3:85476585-85506719 (-)
BALB/cJ ENSMUSG00180041415
 protein coding gene Chr3:85658163-85688319 (-)
C3H/HeJ ENSMUSG00175037225
 protein coding gene Chr3:85454701-85484829 (-)
C57BL/6NJ ENSMUSG00215049005
 protein coding gene Chr3:85894668-85925137 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025179
 protein coding gene Chr3:81523135-81554123 (-)
CAST/EiJ ENSTCUG00005047356
 protein coding gene Chr3:84972054-85002396 (-)
CBA/J ENSMUSG00210038784
 protein coding gene Chr3:85592391-85622518 (-)
DBA/2J ENSMUSG00185050246
 protein coding gene Chr3:85746709-85776863 (-)
FVB/NJ ENSMUSG00205048887
 protein coding gene Chr3:84516322-84546439 (-)
JF1/MsJ ENSUMUG00000015454
 protein coding gene Chr3:85254841-85396588 (-)
LP/J ENSMUSG00230027082
 protein coding gene Chr3:87728276-87758741 (-)
NOD/ShiLtJ ENSMUSG00190043409
 protein coding gene Chr3:85977157-86007642 (-)
NZO/HlLtJ ENSMUSG00225006456
 protein coding gene Chr3:90483666-90513794 (-)
PWK/PhJ ENSLUMG00010045580
 protein coding gene Chr3:85346107-85376042 (-)
SPRET/EiJ ENSMSPG00010047698
 protein coding gene Chr3:86196598-86281025 (-)
WSB/EiJ ENSIUOG00005046925
 protein coding gene Chr3:86005574-86036064 (-)



Homology
more
  • Human Ortholog
    SYT11, synaptotagmin 11
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SYT11, synaptotagmin 11
  • Synonyms
    sytXI
  • Links
    NCBI Gene ID: 23208
    UniProt: Q9BT88

  • Chr Location
    1q22; chr1:155859449-155885199 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    16 phenotype references
Homozygous mutation of this gene results in no obvious abnormal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    126
  • GO References
    18
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    742
  • Tissues
    145
  • cDNA Data
    14
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 229521 NCBI Gene Model | MGI Sequence Detail 30461 C57BL/6J ±  kb
transcript NM_018804 RefSeq | MGI Sequence Detail 4585 ZRU/MplStud  
polypeptide Q9R0N3 UniProt | EBI | MGI Sequence Detail 430 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 15
    Primer pair 1
    Other 1

    Microarray probesets 10
Other
Accession IDs
less
MGI:1923498, MGI:2139826
References
more
  • Summaries
    All 60
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 18
    Phenotypes 16
  • Earliest
    J:62060 Fukuda M, et al., Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X. J Biol Chem. 1999 Oct 29;274(44):31421-7
  • Latest
    J:369839 Wang Y, et al., Synaptotagmin-11 Inhibits Synaptic Vesicle Endocytosis via Endophilin A1. J Neurosci. 2023 Sep 6;43(36):6230-6248
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory